SCHEMBL10092004

SCHEMBL10092004

C=C1CSCC(OC(=O)c2ccc(Br)cc2)CSC1

nearest known ligand 0.68

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 15/20 0.68
PTPN2 P17706 13/20 0.68
PTPRF P10586 1/20 0.68
NPSR1 Q6W5P4 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
PTPN6 P29350 6/20 0.43
PTPN11 Q06124 6/20 0.43
KDM4E B2RXH2 1/20 0.39
ALDH1A1 P00352 1/20 0.39
POLB P06746 1/20 0.39
TSHR P16473 1/20 0.39
HSD17B10 Q99714 1/20 0.39
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10092009 0.92 PTPN1 (0.54) PTPN1PTPN2PTPRFNPSR1PTPN6
SCHEMBL10092182 0.85 PTPN1 (0.48) PTPN1PTPN2PTPRFNPSR1PTPN6
SCHEMBL10092005 0.85 CHRNA7 (0.48) PTPN1PTPN2PTPRFPTPN6PTPN11
SCHEMBL14039909 0.82 PTPN1 (0.53) PTPN1PTPN2PTPRFPTPN6PTPN11
SCHEMBL10092120 0.77 KDM4E (0.54) PTPN1PTPN2PTPRFPTPN6PTPN11
SCHEMBL27964590 0.76 PTPN2 (0.71) PTPN1PTPN2PTPRFNPSR1MEN1
SCHEMBL27517068 0.73 PTPRF (0.67) PTPN1PTPN2PTPRFNPSR1L3MBTL1
SCHEMBL13169508 0.71 PTPRF (0.65) PTPN1PTPN2PTPRFNPSR1ALDH1A1
SCHEMBL16383373 0.71 KDM4E (0.33) KDM4EALDH1A1POLBTSHRHSD17B10
SCHEMBL13126225 0.71 KMT2A (0.44) PTPN1PTPN2PTPRFL3MBTL1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120019938-A1 CURABLE RESIN COMPOSITION FOR CEMENTED LENS, IMAGING LENS, AND METHOD FOR MANUFACTURING IMAGING LENS FUJIFILM CORPORATION (JP) 2012-01-26 US disclosed