SCHEMBL10092182

SCHEMBL10092182

Bc1ccc(C(=O)OC2CSCC(=C)CSC2)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 10/20 0.48
PTPN2 P17706 9/20 0.48
PTPRF P10586 2/20 0.48
PTPN6 P29350 4/20 0.43
PTPN11 Q06124 4/20 0.43
ALDH1A1 P00352 2/20 0.39
KDM4E B2RXH2 1/20 0.39
POLB P06746 1/20 0.39
TSHR P16473 1/20 0.39
HSD17B10 Q99714 1/20 0.39
SENP8 Q96LD8 2/20 0.36
SENP6 Q9GZR1 2/20 0.36
LMNA P02545 2/20 0.36
CASP3 P42574 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
SCN1A P35498 2/20 0.35
SCN2A Q99250 2/20 0.35
SCN3A Q9NY46 2/20 0.35
STS P08842 2/20 0.34
MAPT P10636 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10092009 0.92 PTPN1 (0.54) PTPN1PTPN2PTPRFPTPN6PTPN11
SCHEMBL10092004 0.85 PTPN1 (0.68) PTPN1PTPN2PTPRFPTPN6PTPN11
SCHEMBL10092005 0.85 CHRNA7 (0.48) PTPN1PTPN2PTPRFPTPN6PTPN11
SCHEMBL14039909 0.82 PTPN1 (0.53) PTPN1PTPN2PTPRFPTPN6PTPN11
SCHEMBL10092120 0.71 KDM4E (0.54) PTPN1PTPN2PTPRFPTPN6PTPN11
SCHEMBL16383373 0.71 KDM4E (0.33) ALDH1A1KDM4EPOLBTSHRHSD17B10
SCHEMBL10092104 0.70 CHRNA7 (0.38) PTPN1PTPN2PTPRFALDH1A1TSHR
SCHEMBL12066323 0.69 PTPN2 (0.40) PTPN1PTPN2PTPRFPTPN6PTPN11
SCHEMBL12901922 0.69 PTPN2 (0.40) PTPN1PTPN2PTPRFPTPN6PTPN11
SCHEMBL13981756 0.68 KDM4E (0.32) ALDH1A1KDM4EPOLBTSHRHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120019938-A1 CURABLE RESIN COMPOSITION FOR CEMENTED LENS, IMAGING LENS, AND METHOD FOR MANUFACTURING IMAGING LENS FUJIFILM CORPORATION (JP) 2012-01-26 US disclosed