SCHEMBL10095155

SCHEMBL10095155

O=C1NC(=O)C(=Cc2cccc3cccc(C(=O)O)c23)C(=O)N1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
METAP1 P53582 2/20 0.47
HSD17B10 Q99714 1/20 0.46
XDH P47989 1/20 0.43
SIRT2 Q8IXJ6 1/20 0.43
SIRT1 Q96EB6 1/20 0.43
MAPT P10636 7/20 0.42
ALDH1A1 P00352 5/20 0.42
KDM4E B2RXH2 5/20 0.42
GAA P10253 1/20 0.42
KMT2A Q03164 7/20 0.41
MEN1 O00255 5/20 0.41
MAPK1 P28482 3/20 0.41
PKM P14618 3/20 0.41
MITF O75030 1/20 0.41
CYP1A2 P05177 1/20 0.41
CYP2C9 P11712 1/20 0.41
RAB9A P51151 1/20 0.41
CCR6 P51684 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
TDP1 Q9NUW8 3/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12014058 0.78 SIRT2 (0.47) METAP1XDHSIRT2SIRT1MAPT
SCHEMBL1248985 0.77 KMT2A (0.59) ALDH1A1KDM4EKMT2AMEN1TDP1
SCHEMBL1248983 0.77 KMT2A (0.59) ALDH1A1KDM4EKMT2AMEN1TDP1
SCHEMBL12892107 0.77 KMT2A (0.59) ALDH1A1KDM4EKMT2AMEN1TDP1
SCHEMBL1506769 0.75 HSD17B10 (0.58) HSD17B10MAPTALDH1A1KDM4EKMT2A
SCHEMBL7624693 0.74 HSD17B10 (0.78) HSD17B10MAPTALDH1A1KDM4EKMT2A
Benzene SCHEMBL28110156 0.74 HSD17B10 (0.78) HSD17B10MAPTALDH1A1KDM4EKMT2A
SCHEMBL68291 0.74 HSD17B10 (0.78) HSD17B10MAPTALDH1A1KDM4EKMT2A
SCHEMBL29404347 0.74 HSD17B10 (0.78) HSD17B10MAPTALDH1A1KDM4EKMT2A
SCHEMBL15106625 0.74 METAP1 (0.49) METAP1XDHMAPTALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2036957-B1 Pigment dispersion liquid, curable composition, color filter, produced using the same, and solid state imaging device FUJIFILM CORP (JP) 2012-01-11 EP disclosed
US-8008364-B2 Curable composition FUJIFILM CORPORATION (JP) 2011-08-30 US disclosed
US-20090017273-A1 PIGMENT DISPERSION LIQUID, CURABLE COMPOSITION, COLOR FILTER PRODUCED USING THE SAME, AND SOLID STATE IMAGING DEVICE FUJIFILM CORPORATION (JP) 2009-01-15 US disclosed