SCHEMBL1506769

SCHEMBL1506769

C=Cc1cccc2cccc(C(=O)O)c12

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 2/20 0.58
NR4A1 P22736 1/20 0.46
NR4A2 P43354 1/20 0.46
NR4A3 Q92570 1/20 0.46
ALDH1A1 P00352 4/20 0.41
CYP1A2 P05177 2/20 0.41
ALOX15 P16050 1/20 0.41
KDM4E B2RXH2 3/20 0.41
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
TSHR P16473 2/20 0.41
RXFP1 Q9HBX9 1/20 0.41
CDC25B P30305 1/20 0.41
KEAP1 Q14145 1/20 0.41
MAPT P10636 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
PTPN1 P18031 1/20 0.40
LMNA P02545 1/20 0.39
CYP2C9 P11712 1/20 0.38
CA12 O43570 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29563927 0.83 HSD17B10 (0.60) HSD17B10NR4A1NR4A2NR4A3ALDH1A1
SCHEMBL1688876 0.83 HSD17B10 (0.60) HSD17B10NR4A1NR4A2NR4A3ALDH1A1
SCHEMBL890497 0.83 HSD17B10 (0.51) HSD17B10NR4A1NR4A2NR4A3ALDH1A1
Acrylic Acid SCHEMBL29270063 0.81 LMNA (0.40) HSD17B10ALDH1A1CYP1A2ALOX15KDM4E
Propene SCHEMBL27695613 0.81 HSD17B10 (0.62) HSD17B10NR4A1NR4A2NR4A3ALDH1A1
Ethylene SCHEMBL3993074 0.80 HSD17B10 (0.72) HSD17B10NR4A1NR4A2NR4A3ALDH1A1
Ethylene SCHEMBL6253400 0.80 HSD17B10 (0.72) HSD17B10NR4A1NR4A2NR4A3ALDH1A1
SCHEMBL29404347 0.80 HSD17B10 (0.78) HSD17B10NR4A1NR4A2NR4A3ALDH1A1
SCHEMBL7624693 0.80 HSD17B10 (0.78) HSD17B10NR4A1NR4A2NR4A3ALDH1A1
Benzene SCHEMBL28110156 0.80 HSD17B10 (0.78) HSD17B10NR4A1NR4A2NR4A3ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8822588-B2 Fluorine-containing polymer and anti-static agent wherein same is used CENTRAL GLASS COMPANY, LIMITED (JP) 2014-09-02 US disclosed
US-8513457-B2 Fluorine-containing compound, fluorine-containing polymer, negative-type resist composition, and patterning process using same CENTRAL GLASS COMPANY, LIMITED (JP) 2013-08-20 US disclosed
EP-2289954-B1 FLUORINE-CONTAINING POLYMER AND ANTI-STATIC AGENT WHEREIN SAME IS USED CENTRAL GLASS CO LTD (JP) 2013-01-16 EP disclosed
US-20120226070-A1 Fluorine-Containing Compound, Fluorine-Containing Polymer, Negative-Type Resist Composition, and Patterning Process Using Same CENTRAL GLASS COMPANY, LIMITED (JP) 2012-09-06 US disclosed
US-8187787-B2 Fluorine-containing compound, fluorine-containing polymer, negative-type resist composition, and patterning process using same CENTRAL GLASS COMPANY, LIMITED (JP) 2012-05-29 US disclosed
US-20110065857-A1 Fluorine-Containing Polymer and Anti-Static Agent Wherein Same is Used CENTRAL GLASS COMPANY, LIMITED (JP) 2011-03-17 US disclosed
EP-2289954-A1 FLUORINE-CONTAINING POLYMER AND ANTI-STATIC AGENT WHEREIN SAME IS USED Central Glass Company, Limited (JP) 2011-03-02 EP disclosed
US-20090011199-A1 Fluorine-Containing Compound, Fluorine-Containing Polymer, Negative-Type Resist Composition, and Patterning Process Using Same CENTRAL GLASS COMPANY, LIMITED (JP) 2009-01-08 US disclosed
EP-0849634-B1 Radiation sensitive resin composition JSR CORP (JP) 2004-03-31 EP disclosed
US-6322949-B2 SULFONIUM COMPOUND AS PHOTOACID GENERATOR JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 2001-11-27 US disclosed
US-20010014427-A1 Radiation sensitive resin composition JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 2001-08-16 US disclosed
US-6187504-B1 PHOTOSENSITIVE BLEND CONTAINING A NAPHTHALENE SULFONIUM SULFONATE DERIVATIVE PHOTOACID GENERATOR, RESIN HAVING ALKALI INSOLUBLE GROUPS CLEAVABLE BY ACID, AN ALKALI SOLUBLE RESIN AND A SOLUBILITY CONTROL AGENT; POSITIVES, RESOLUTION JSR CORPORATION (JP) 2001-02-13 US disclosed
EP-0849634-A1 Radiation sensitive resin composition JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1998-06-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120226070-A1 Fluorine-Containing Compound, Fluorine-Containing Polymer, Negative-Type Resist Composition, and Patterning Process Using Same RTF1, FGFR2, FGFR1 HSD17B10 3788/4885NR4A1 1993/4885NR4A2 2289/4885
US-20090011199-A1 Fluorine-Containing Compound, Fluorine-Containing Polymer, Negative-Type Resist Composition, and Patterning Process Using Same FGFR2, RTF1, ADGRF1 HSD17B10 3780/4885NR4A1 2593/4885NR4A2 2856/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.