SCHEMBL1009653

SCHEMBL1009653

N#CN1CCNCC1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL27877920 0.97
SCHEMBL27777415 0.85 CTSL (0.40)
SCHEMBL22048399 0.82
Pyridine SCHEMBL28232783 0.80 PLD1 (0.38)
SCHEMBL11645574 0.75
SCHEMBL5319426 0.71
SCHEMBL3428433 0.69
SCHEMBL5729123 0.69
SCHEMBL11221018 0.69
SCHEMBL8466 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 194 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115038700-A Gem disubstituted heterocyclic compounds and their use as IDH inhibitors 内尔维亚诺医疗科学公司 2022-09-09 CN claimed
CN-114015342-A Antistatic scratch-resistant automobile paint and preparation method thereof 黄超财 2022-02-08 CN claimed
US-20200087264-A1 NOVEL SELECTIVE LIGAND FOR DOPAMINE D3 RECEPTOR, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL APPLICATION THEREOF Shenzhen City Linglan Bio-Pharmaceutical Technology Co., Ltd (CN) 2020-03-19 US claimed
CN-109311889-A Activin receptor-like kinase inhibitors 蓝图药品公司 2019-02-05 CN claimed
CN-109071563-A Inhibitors of bruton's tyrosine kinase and methods of use thereof 詹森药业有限公司 2018-12-21 CN claimed
CN-108601747-A Abuse-resistant transdermal delivery device for the treatment of pain and composition comprising an opioid agonist and an N-oxide derivative of an opioid antagonist that is not transdermally delivered 欧洲凯尔特公司 2018-09-28 CN claimed
CN-106103416-A Azaspiro derivant as TRPM8 antagonist 拉夸里亚创药株式会社 2016-11-09 CN claimed
CN-101883492-A Rodenticidal mixture BASF SE 2010-11-10 CN claimed
EP-1745033-A4 4,5-DISUBSTITUTED-2-ARYL PYRIMIDINES NEUROGEN CORP (US) 2009-08-26 EP claimed
CN-101453994-A Extended release multi-particulate oral pharmaceutical dosage form FLAMEL TECH SA (FR) 2009-06-10 CN claimed
EP-1745033-A2 4,5-DISUBSTITUTED-2-ARYL PYRIMIDINES NEUROGEN CORPORATION (US) 2007-01-24 EP claimed
WO-2005110416-A2 4,5-DISUBSTITUTED-2-ARYL PYRIMIDINES NEUROGEN CORPORATION (US) 2005-11-24 WO claimed
CN-1627938-A Pharmaceutical dosage form for transmucosal delivery PHARMACIA CORP (US) 2005-06-15 CN claimed
US-4925901-A STORAGE STAABILITY, ONIUM ION CATALYST THE DOW CHEMICAL COMPANY (US) 1990-05-15 US claimed
EP-0008475-B2 A PROCESS FOR PREPARING PEROXIDE-BASED BLEACH MEDIA AND CONCENTRATED BLEACH COMPOSITIONS FOR USE IN CARRYING OUT THAT PROCESS SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1988-02-24 EP claimed
EP-0008475-B1 A PROCESS FOR PREPARING PEROXIDE-BASED BLEACH MEDIA AND CONCENTRATED BLEACH COMPOSITIONS FOR USE IN CARRYING OUT THAT PROCESS SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1981-12-16 EP claimed
US-4199466-A CYANOAMINES SHELL OIL COMPANY (US) 1980-04-22 US claimed
EP-0008475-A1 A process for preparing peroxide-based bleach media and concentrated bleach compositions for use in carrying out that process SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1980-03-05 EP claimed
US-20260092074-A1 Annelated Pyridines as Steroidogenesis Inhibitors, Preparation Method and Use Thereof GUANGZHOU VINNOCENT PHARMACEUTICAL LTD (CN) 2026-04-02 US disclosed
US-4062844-A Process for preparing hypotensive 2-(4-aroylpiperazin-1-yl)-amino-6,7-dimethoxyquinazolines PFIZER INC. (US) 1977-12-13 US disclosed