SCHEMBL1009702

SCHEMBL1009702

O=P(F)(Cl)Oc1ccc(F)cc1

nearest known ligand 0.50

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.50
CYP2C9 P11712 1/20 0.50
CYP2C19 P33261 1/20 0.50
HPGD P15428 3/20 0.49
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
SMN1; SMN2 Q16637 2/20 0.38
MAPK1 P28482 1/20 0.38
CYP3A4 P08684 1/20 0.37
TSHR P16473 1/20 0.37
MAPT P10636 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
SOS1 Q07889 1/20 0.35
HSPB1 P04792 1/20 0.35
LMNA P02545 2/20 0.33
NFE2L2 Q16236 1/20 0.33
S1PR2 O95136 1/20 0.33
NPC1 O15118 1/20 0.32
RAB9A P51151 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1809191 0.84 CYP1A2 (0.47) CYP1A2CYP2C9CYP2C19HPGDMEN1
SCHEMBL14055537 0.81 HPGD (0.52) CYP1A2CYP2C9CYP2C19HPGDMEN1
SCHEMBL19348724 0.80 CYP3A4 (0.61) CYP1A2CYP2C9CYP2C19HPGDMEN1
SCHEMBL8519279 0.80 CYP2C19 (0.45) CYP1A2CYP2C9CYP2C19HPGDMEN1
SCHEMBL1011207 0.79 SRC (0.54) HPGDMEN1KMT2ALMNA
SCHEMBL13280266 0.78 CYP3A4 (0.58) CYP1A2CYP2C9CYP2C19HPGDMEN1
SCHEMBL4946779 0.77 HPGD (0.49) CYP1A2CYP2C9CYP2C19HPGDSMN1; SMN2
SCHEMBL1807898 0.76 CYP3A4 (0.45) CYP1A2CYP2C9CYP2C19HPGDMEN1
SCHEMBL790308 0.74 CYP1A2 (0.40) CYP1A2CYP2C9CYP2C19HPGDMEN1
SCHEMBL17169180 0.74 CES2 (0.53) CYP1A2CYP2C9CYP2C19HPGDSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1798792-B1 NONAQUEOUS ELECTROLYTE SOLUTION, AND NONAQUEOUS ELECTROLYTE BATTERY HAVING SAME BRIDGESTONE CORP (JP) 2011-01-05 EP disclosed
US-20080153005-A1 Non-Aqueous Electrolyte and Non-Aqueous Electrolyte Battery Comprising the Same BRIDGESTONE CORPORATION (JP) 2008-06-26 US disclosed
EP-1798792-A1 NONAQUEOUS ELECTROLYTE SOLUTION, AND NONAQUEOUS ELECTROLYTE BATTERY HAVING SAME Bridgestone Corporation (JP) 2007-06-20 EP disclosed