Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | GSR | P00390 | 1/20 | 0.39 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.39 |
| ▸ | CPB2 | Q96IY4 | 4/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.38 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | LCK | P06239 | 1/20 | 0.37 |
| ▸ | PPARD | Q03181 | 1/20 | 0.37 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.37 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.37 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.34 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.34 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.33 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1010539 | 1.00 | MAPT (0.41) | MAPTGSRTBXAS1CPB2GPR84 | |
| SCHEMBL21073899 | 0.86 | GPR84 (0.46) | MAPTGSRTBXAS1CPB2GPR84 | |
| SCHEMBL9009694 | 0.86 | GPR84 (0.46) | MAPTGSRTBXAS1CPB2GPR84 | |
| SCHEMBL30018402 | 0.86 | GPR84 (0.46) | MAPTGSRTBXAS1CPB2GPR84 | |
| SCHEMBL30018584 | 0.86 | GPR84 (0.46) | MAPTGSRTBXAS1CPB2GPR84 | |
| SCHEMBL28261795 | 0.86 | GPR84 (0.46) | MAPTGSRTBXAS1CPB2GPR84 | |
| SCHEMBL3613866 | 0.86 | GPR84 (0.46) | MAPTGSRTBXAS1CPB2GPR84 | |
| SCHEMBL12851496 | 0.83 | GSR (0.43) | MAPTGSRTBXAS1GPR84RNPEP | |
| SCHEMBL15319080 | 0.83 | MAPT (0.34) | MAPTGSRTBXAS1CPB2GPR84 | |
| SCHEMBL6944529 | 0.80 | MAPT (0.65) | MAPTGSRCPB2GPR84RNPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2268319-A2 | PRECURSORS OF LIPID METABOLISM FOR THE DIAGNOSIS AND TREATMENT OF CANCER | Universität Ulm (DE) | 2011-01-05 | — | — | EP | disclosed |
| WO-2009109798-A2 | PRECURSORS OF LIPID METABOLISM FOR THE DIAGNOSIS AND TREATMENT OF CANCER | UNIVERSITÄT ULM (DE) | 2009-09-11 | — | — | WO | disclosed |