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GPR84

G-protein coupled receptor 84 · Q9NQS5 · GPR84 on Sugi Atlas →

231,603 patent compounds predicted against GPR84, 116,499 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
SCHEMBL36143 SCHEMBL36143 0.50 11/20
SCHEMBL17773 SCHEMBL17773 0.71 10/20
SCHEMBL22240 SCHEMBL22240 0.64 10/20
SCHEMBL22513 SCHEMBL22513 0.64 10/20
SCHEMBL61656 SCHEMBL61656 0.62 10/20
SCHEMBL60937 SCHEMBL60937 0.61 10/20
Valeric Acid Valeric Acid (SCHEMBL29915) 0.54 10/20
SCHEMBL61937 SCHEMBL61937 0.53 10/20
SCHEMBL62370 SCHEMBL62370 0.53 10/20
Propylthiouracil Propylthiouracil (SCHEMBL41239) 0.49 10/20
Nile Red Nile Red (SCHEMBL49047) 0.47 10/20
SCHEMBL56792 SCHEMBL56792 0.45 10/20
SCHEMBL62437 SCHEMBL62437 0.40 10/20
SCHEMBL62448 SCHEMBL62448 0.39 10/20
SCHEMBL20641 SCHEMBL20641 0.67 9/20
SCHEMBL16113 SCHEMBL16113 1.00 8/20
SCHEMBL28125 SCHEMBL28125 1.00 8/20
Hexanoate Hexanoate (SCHEMBL48781) 0.76 8/20
Octanedioate Octanedioate (SCHEMBL3301) 0.75 8/20
Azelaic Acid Azelaic Acid (SCHEMBL3887) 0.75 8/20

Clinical trials — most relevant to GPR84 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Investigating the Potential Role of Aerosolized Retinoic Acid, a Potent Vitamin A Metabolite for Treating COVID-19 Anosmia and Retinoic Acid Insufficiency .A Novel Approach for Regaining Sense of Smell. PHASE4UNKNOWN
A Series of Pilot Studies to Evaluate the haemoDynamic and mEtabolic Effects oF apelIn aNd rElaxin PHASE2UNKNOWN
A Safety and Efficacy Study of Carbidopa-levodopa in Patients With Macular Degeneration PHASE2WITHDRAWN
Mediterranean Diet and Inequality in Early Breast Cancer PHASE2RECRUITING
Studying the Influence of LEAP2 on Integrated Endocrine Control of Eating During Semaglutide Treatment PHASE1/PHASE2RECRUITING
Sweet Taste Receptors and the Secretion of Glucagon-like Peptide-1 and Peptide YY PHASE1COMPLETED
Role of the Gut Sweet Taste Receptor in the Secretion of Glucagon-like Peptide-1 and Peptide YY PHASE1COMPLETED
Role of the Gut Sweet Taste Receptor in the Secretion of Satiation Peptides PHASE1COMPLETED
Remote Ischaemic Conditioning in Endovascular Recanalization for Proximal Anterior Circulation Occlusion Study PHASE1UNKNOWN
The Role of Endocannabinoids in Insulin Production and Action PHASE1COMPLETED
Hyperlactacidemia in Major Abdominal Surgery and Monocarboxylate Receptors nanUNKNOWN
FFAR Agonist on Incretins, Insulin, Lipids and Inflammation nanCOMPLETED
Neutrophil FFA2/GPR43 Receptor Expression in Patients With the Diagnosis of Sepsis nanWITHDRAWN
Dose-response Effect of Pine Nut Oil as a Dual FFA1 and FFA4 Agonist on Glucose Tolerance in Healthy Humans. nanCOMPLETED
Oat Bran and Plasma Lipid and Fecal Bacteria in Coronary Artery Disease Patients nanCOMPLETED
-Oleoyl Glycerol is a GPR119 Agonist and Signals GLP-1 Release in Humans. nanCOMPLETED
Effect of Dietary Oils as G-protein-coupled Receptor Agonists on Glucose Tolerance nanUNKNOWN
Colonic Propionate, Appetite, and Weight Loss nanCOMPLETED
The Role of Stromal Cell-Derived Factor-1 (SDF-1)/CXC Chemokine Receptor 4 (CXCR4) in Metastasis of Laryngeal and Hypopharyngeal Squamous Cell Carcinoma nanUNKNOWN
GPR109A and Parkinson's Disease: Role of Niacin in Outcome Measures nanCOMPLETED
Fat-induced Release of GLP-1 in Humans nanCOMPLETED
Gastroparesis Registry 3 nanCOMPLETED
The Application of 68Ga-Pentixafor Alongside 68Ga-FAPI-04 PET/MR for Assessing Primary Aldosteronism. nanNOT_YET_RECRUITING
Effects of Probiotics on Gut Microbiota, Endocannabinoid and Immune Activation and Symptoms of Fatigue in Dancers nanCOMPLETED
RCT to Describe the Effects of Colon Delivered Acetate, Propionate and Butyrate on Satiety and Glucose Homeostasis nanCOMPLETED
Assessment of CXCL5 Level in SLE Patients and Its Correlation with Disease Activity nanNOT_YET_RECRUITING
Selective Activation of the Adrenomedullin Receptors in Migraine nanNOT_YET_RECRUITING
Intravenous Terbutaline in Severe Status Asthmaticus nanUNKNOWN
Acute Asthma Responsiveness and B2 Adrenergic Receptors Polymorphisms nanCOMPLETED
Development of Therapeutic Approaches Modulating Molecular Targets Implicated on Cancer Stem Cell-related Aggressiveness nanUNKNOWN

Related proteins — ESM-2 sequence neighbours (a GPR84 binder may also engage these)

ProteinNameSimilarity
Q2KI97 — 1.000 Q2KI97 →
Q8CIM5 — 0.998 Q8CIM5 →
P49219 — 0.993 P49219 →
P49287 — 0.990 P49287 →
Q16950 — 0.990 Q16950 →
P51046 — 0.989 P51046 →
Q8CIQ6 — 0.989 Q8CIQ6 →
Q91081 — 0.989 Q91081 →
O70528 — 0.988 O70528 →
Q62758 — 0.988 Q62758 →
Q25190 — 0.988 Q25190 →
P97288 — 0.987 P97288 →
P49285 — 0.987 P49285 →
P18901 — 0.987 P18901 →
MTNR1B Melatonin receptor type 1B 0.987 landscape →
HTR4 5-hydroxytryptamine receptor 4 0.987 landscape →
MTNR1A Melatonin receptor type 1A 0.986 landscape →
O42384 — 0.986 O42384 →
Q8JG69 — 0.986 Q8JG69 →
Q6XXX9 — 0.986 Q6XXX9 →
P51049 — 0.985 P51049 →
DRD1 D(1A) dopamine receptor 0.985 landscape →
P48040 — 0.985 P48040 →
Q8TDV0 — 0.985 Q8TDV0 →
Q6SW98 — 0.985 Q6SW98 →
Q9N297 — 0.985 Q9N297 →
P50130 — 0.985 P50130 →
P31390 — 0.985 P31390 →
Q6XXY0 — 0.985 Q6XXY0 →
P49288 — 0.985 P49288 →