Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMP | P19971 | 1/20 | 0.65 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | ALB | P02768 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | STING1 | Q86WV6 | 3/20 | 0.48 |
| ▸ | POLA1 | P09884 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
| ▸ | PNP | P00491 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.47 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13239716 | 1.00 | TYMP (0.65) | TYMPLMNAALDH1A1ALBMAPK1 | |
| SCHEMBL12352411 | 1.00 | TYMP (0.65) | TYMPLMNAALDH1A1ALBMAPK1 | |
| Deoxyinosine SCHEMBL25819948 | 0.90 | TYMP (0.66) | TYMPLMNAALDH1A1ALBMAPK1 | |
| Deoxyinosine SCHEMBL5982287 | 0.90 | TYMP (0.66) | TYMPLMNAALDH1A1ALBMAPK1 | |
| Deoxyinosine SCHEMBL12222465 | 0.90 | TYMP (0.66) | TYMPLMNAALDH1A1ALBMAPK1 | |
| Deoxyinosine SCHEMBL24308 | 0.90 | TYMP (0.66) | TYMPLMNAALDH1A1ALBMAPK1 | |
| Deoxyinosine SCHEMBL889715 | 0.90 | TYMP (0.66) | TYMPLMNAALDH1A1ALBMAPK1 | |
| Deoxyinosine SCHEMBL12570174 | 0.90 | TYMP (0.66) | TYMPLMNAALDH1A1ALBMAPK1 | |
| SCHEMBL26757542 | 0.88 | TYMP (0.70) | TYMPLMNAALDH1A1ALBMAPK1 | |
| SCHEMBL26757236 | 0.88 | TYMP (0.70) | TYMPLMNAALDH1A1ALBMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2415776-A1 | Beta-L-2'-Deoxy-Nucleosides for the Treatment of Hepatitis B | IDENIX Pharmaceuticals, Inc. (US) | 2012-02-08 | — | — | EP | disclosed |