Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMP | P19971 | 1/20 | 0.66 |
| ▸ | LMNA | P02545 | 2/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.65 |
| ▸ | ALB | P02768 | 1/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.65 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.59 |
| ▸ | PNP | P00491 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.58 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.58 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.58 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.58 |
| ▸ | PIM1 | P11309 | 1/20 | 0.55 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.55 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.55 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.55 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Deoxyinosine SCHEMBL24308 | 1.00 | TYMP (0.66) | TYMPLMNAALDH1A1ALBMAPK1 | |
| Deoxyinosine SCHEMBL5982287 | 1.00 | TYMP (0.66) | TYMPLMNAALDH1A1ALBMAPK1 | |
| Deoxyinosine SCHEMBL12570174 | 1.00 | TYMP (0.66) | TYMPLMNAALDH1A1ALBMAPK1 | |
| Deoxyinosine SCHEMBL12222465 | 1.00 | TYMP (0.66) | TYMPLMNAALDH1A1ALBMAPK1 | |
| Deoxyinosine SCHEMBL889715 | 1.00 | TYMP (0.66) | TYMPLMNAALDH1A1ALBMAPK1 | |
| SCHEMBL13239716 | 0.90 | TYMP (0.65) | TYMPLMNAALDH1A1ALBMAPK1 | |
| SCHEMBL12352411 | 0.90 | TYMP (0.65) | TYMPLMNAALDH1A1ALBMAPK1 | |
| SCHEMBL10098564 | 0.90 | TYMP (0.65) | TYMPLMNAALDH1A1ALBMAPK1 | |
| SCHEMBL22458562 | 0.87 | LMNA (0.64) | TYMPLMNAALDH1A1ALBMAPK1 | |
| SCHEMBL22388704 | 0.87 | ALDH1A1 (0.57) | TYMPLMNAALDH1A1ALBMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230212572-A1 | Guanosine Analogues for Use in Therapeutics Polynucleotides | ROCHE INNOVATION CENTER COPENHAGEN A/S (DK) | 2023-07-06 | — | — | US | disclosed |