Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 1/20 | 0.47 |
| ▸ | ACACA | Q13085 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.36 |
| ▸ | CPT2 | P23786 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ACLY | P53396 | 1/20 | 0.36 |
| ▸ | ARG1 | P05089 | 3/20 | 0.32 |
| ▸ | ARG2 | P78540 | 2/20 | 0.32 |
| ▸ | ODC1 | P11926 | 1/20 | 0.32 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.31 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.30 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1890992 | 0.84 | ACACB (0.35) | ACACBACACAMAPTODC1BLM | |
| SCHEMBL1010543 | 0.82 | ACACB (0.53) | ACACBACACAMAPTFFAR1CPT2 | |
| SCHEMBL526121 | 0.75 | FFAR1 (0.41) | ACACBACACAMAPTFFAR1CPT2 | |
| SCHEMBL29496308 | 0.75 | FFAR1 (0.41) | ACACBACACAMAPTFFAR1CPT2 | |
| SCHEMBL22268722 | 0.74 | ACACB (0.33) | ACACBACACA | |
| SCHEMBL5474459 | 0.73 | ALDH1A1 (0.42) | ACACBACACAFFAR1CPT2TDP1 | |
| SCHEMBL1010557 | 0.73 | ACACB (0.40) | ACACBACACAFFAR1CPT2TDP1 | |
| SCHEMBL5859353 | 0.73 | GGPS1 (0.50) | FFAR1TDP1GPR84 | |
| SCHEMBL10339977 | 0.73 | GGPS1 (0.50) | FFAR1TDP1GPR84 | |
| SCHEMBL337569 | 0.73 | GGPS1 (0.50) | FFAR1TDP1GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2268319-A2 | PRECURSORS OF LIPID METABOLISM FOR THE DIAGNOSIS AND TREATMENT OF CANCER | Universität Ulm (DE) | 2011-01-05 | — | — | EP | disclosed |
| WO-2009109798-A2 | PRECURSORS OF LIPID METABOLISM FOR THE DIAGNOSIS AND TREATMENT OF CANCER | UNIVERSITÄT ULM (DE) | 2009-09-11 | — | — | WO | disclosed |