Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CA3 | P07451 | 2/20 | 0.39 |
| ▸ | CA5A | P35218 | 2/20 | 0.39 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA6 | P23280 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23366306 | 0.82 | ALDH1A1 (0.56) | ALDH1A1POLBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL8880042 | 0.72 | ALDH1A1 (0.46) | ALDH1A1POLBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL1460181 | 0.70 | ALDH1A1 (0.54) | ALDH1A1POLBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL865926 | 0.69 | — | — | |
| SCHEMBL7771621 | 0.69 | ALDH1A1 (0.52) | ALDH1A1POLBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL3869183 | 0.69 | ALDH1A1 (0.52) | ALDH1A1POLBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL130951 | 0.69 | ALDH1A1 (0.52) | ALDH1A1POLBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL22092385 | 0.69 | ALDH1A1 (0.52) | ALDH1A1POLBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL9138159 | 0.69 | ALDH1A1 (0.52) | ALDH1A1POLBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL21814803 | 0.67 | ALDH1A1 (0.50) | ALDH1A1POLBSMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7270808-B2 | Having covalently coupled bioactive agent and targeting ligand; controlled release; stability, solubility; reduced toxicity | INSERT THERAPEUTICS, INC. (US) | 2007-09-18 | — | — | US | disclosed |