SCHEMBL10099644

SCHEMBL10099644

CN(c1ccccc1)c1nc(N(c2ccccc2)c2ccccc2)nc(N(c2ccccc2)c2ccccc2)n1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.55
TDP1 Q9NUW8 1/20 0.55
MAPT P10636 4/20 0.53
TSHR P16473 4/20 0.47
LMNA P02545 2/20 0.47
MAPK1 P28482 2/20 0.47
L3MBTL1 Q9Y468 2/20 0.47
CYP1A2 P05177 1/20 0.47
CYP3A4 P08684 1/20 0.47
CYP2D6 P10635 1/20 0.47
CYP2C9 P11712 1/20 0.47
CYP2C19 P33261 1/20 0.47
SMN1; SMN2 Q16637 2/20 0.44
MEN1 O00255 1/20 0.44
XBP1 P17861 1/20 0.44
NTSR1 P30989 1/20 0.44
KMT2A Q03164 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44
NPC1 O15118 1/20 0.43
JAK2 O60674 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8974883 0.91 TSHR (0.53) ALDH1A1TSHRLMNAMAPK1L3MBTL1
SCHEMBL77495 0.86 ALDH1A1 (0.70) ALDH1A1TDP1MAPTTSHRLMNA
SCHEMBL14264149 0.81 MERTK (0.52) ALDH1A1LMNAMEN1KMT2ANPSR1
SCHEMBL14264144 0.81 MERTK (0.52) ALDH1A1LMNAMEN1KMT2ANPSR1
SCHEMBL8973771 0.81 ALDH1A1 (0.59) ALDH1A1TDP1MAPTTSHRMAPK1
SCHEMBL17051455 0.80 ALDH1A1 (0.57) ALDH1A1TDP1MAPTTSHRLMNA
SCHEMBL23139603 0.79 TSHR (0.45) TSHRLMNAMAPK1L3MBTL1CYP1A2
SCHEMBL17042383 0.79 MEN1 (0.51) MAPTTSHRLMNAMAPK1L3MBTL1
SCHEMBL11364865 0.79 TSHR (0.45) TSHRLMNAMAPK1L3MBTL1CYP1A2
Cyanate SCHEMBL28109038 0.79 TSHR (0.45) ALDH1A1MAPTTSHRLMNAMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8147638-B2 Polarizing plate and display using the same KONICA MINOLTA OPTO INC. (JP) 2012-04-03 US disclosed
US-8147638-B2 Polarizing plate and display using the same KONICA MINOLTA OPTO INC. (JP) 2012-04-03 US disclosed
US-20110155306-A1 POLARIZING PLATE AND DISPLAY USING THE SAME KONICA MINOLTA OPTO, INC. (JP) 2011-06-30 US disclosed
US-20110155306-A1 POLARIZING PLATE AND DISPLAY USING THE SAME KONICA MINOLTA OPTO, INC. (JP) 2011-06-30 US disclosed
US-7968019-B2 Optical compensation film, method for producing optical compensation film, polarization plate and liquid crystal display KONICA MINOLTA OPTO, INC. (JP) 2011-06-28 US disclosed
US-7968019-B2 Optical compensation film, method for producing optical compensation film, polarization plate and liquid crystal display KONICA MINOLTA OPTO, INC. (JP) 2011-06-28 US disclosed
US-7939002-B2 Retardation film, method for producing the same, polarizing plate and liquid crystal display KONICA MINOLTA OPTO, INC. (JP) 2011-05-10 US disclosed
US-7922947-B2 Method of producing dispersion FUJIFILM CORPORATION (JP) 2011-04-12 US disclosed
US-7854864-B2 Method for manufacturing an optical film having a convexoconcave structure KONICA MINOLTA OPTO, INC. (JP) 2010-12-21 US disclosed
US-7815823-B2 Optical film, manufacturing method of optical film, optical compensating film, manufacturing method of optical compensating film, polarizing plate, and liquid crystal display KONICA MINOLTA OPTO, INC. (JP) 2010-10-19 US disclosed
US-7445821-B2 Cellulose ester film and its manufacturing method, optical film, polarizing plate and liquid crystal display KONICA MINOLTA OPTO, INC. (JP) 2008-11-04 US disclosed
US-20080013173-A1 METHOD OF MANUFACTURING A POLARIZING PLATE PROTECTIVE FILM, POLARIZING PLATE PROTECTIVE FILM, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY DEVICE KONICA MINOLTA OPTO, INC. (JP) 2008-01-17 US disclosed
US-20080013173-A1 METHOD OF MANUFACTURING A POLARIZING PLATE PROTECTIVE FILM, POLARIZING PLATE PROTECTIVE FILM, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY DEVICE KONICA MINOLTA OPTO, INC. (JP) 2008-01-17 US disclosed
US-20070252293-A1 METHOD FOR MANUFACTURING AN OPTICAL FILM HAVING A CONVEXOCONCAVE STRUCTURE, OPTICAL FILM, WIRE GRID POLARIZER AND RETARDATION FILM KONICA MINOLTA OPTO, INC. (JP) 2007-11-01 US disclosed
US-20070134446-A1 Retardation film, method for producing the same, polarizing plate and liquid crystal display KONICA MINOLTA OPTO, INC. 2007-06-14 US disclosed
US-20070097302-A1 RETARDATION FILM, POLARIZING PLATE AND VERTICAL ALIGNMENT MODE LIQUID CRYSTAL DISPLAY KONICA MINOLTA OPTO, INC. (JP) 2007-05-03 US disclosed
US-20070097302-A1 RETARDATION FILM, POLARIZING PLATE AND VERTICAL ALIGNMENT MODE LIQUID CRYSTAL DISPLAY KONICA MINOLTA OPTO, INC. (JP) 2007-05-03 US disclosed
US-20070019133-A1 Polarizing plate and liquid crystal display device KONICA MINOLTA OPTO, INC. (JP) 2007-01-25 US disclosed
US-7166339-B1 Phase contrast plate comprising one sheet of cellulose ester film containing aromatic compound FUJIFILM CORPORATION (JP) 2007-01-23 US disclosed
US-7166339-B1 Phase contrast plate comprising one sheet of cellulose ester film containing aromatic compound FUJIFILM CORPORATION (JP) 2007-01-23 US disclosed