Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 1/20 | 0.50 |
| ▸ | KIT | P10721 | 1/20 | 0.50 |
| ▸ | KDR | P35968 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.46 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.44 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.43 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.43 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10099697 | 0.85 | PDGFRB (0.50) | PDGFRBKITKDRMAPTDCUN1D1 | |
| SCHEMBL8655680 | 0.80 | MAOB (0.47) | PDGFRBKITKDRDCUN1D1DYRK1A | |
| SCHEMBL28289637 | 0.78 | PDGFRB (0.54) | PDGFRBKITKDRMAPTDCUN1D1 | |
| SCHEMBL16481876 | 0.78 | PDGFRB (0.54) | PDGFRBKITKDRMAPTLMNA | |
| SCHEMBL259080 | 0.77 | KDM4E (0.42) | PDGFRBMAPTLMNAKDM4ESMN1; SMN2 | |
| SCHEMBL17843990 | 0.77 | MKNK1 (0.53) | PDGFRBKITKDRMAPTKDM4E | |
| SCHEMBL14736598 | 0.76 | MAPT (0.52) | PDGFRBKITKDRMAPTKDM4E | |
| SCHEMBL7146244 | 0.76 | NR1H2 (0.58) | PDGFRBKITKDRMAPTTDP1 | |
| SCHEMBL15987710 | 0.74 | PDGFRB (0.50) | PDGFRBKITKDRDCUN1D1DYRK1A | |
| SCHEMBL10099715 | 0.74 | PDGFRB (0.48) | PDGFRBKITKDRMAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012007006-A1 | TRIAZOLO- AND PYRAZOLOQUINAZOLINE DERIVATIVES AS PDE10A ENZYME INHIBITOR | H. LUNDBECK A/S (DK) | 2012-01-19 | — | — | WO | disclosed |