Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.47 |
| ▸ | SYK | P43405 | 1/20 | 0.46 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.46 |
| ▸ | KIT | P10721 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.41 |
| ▸ | PTGDR | Q13258 | 2/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.40 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.40 |
| ▸ | ATP4A | P20648 | 1/20 | 0.40 |
| ▸ | ATP4B | P51164 | 1/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8656607 | 0.85 | MAOB (0.43) | MAOBSYKPDGFRBTLR8TAAR1 | |
| SCHEMBL5674038 | 0.81 | MAOA (0.43) | TLR8TAAR1 | |
| SCHEMBL10099698 | 0.80 | PDGFRB (0.50) | PDGFRBKITKDRDCUN1D1ADORA2A | |
| SCHEMBL10099697 | 0.80 | PDGFRB (0.50) | PDGFRBKITKDRDCUN1D1PTGDR | |
| SCHEMBL1927324 | 0.79 | MAOA (0.42) | TLR8TAAR1 | |
| SCHEMBL11097956 | 0.76 | SSTR1 (0.43) | SYKTAAR1ADORA2A | |
| SCHEMBL4861236 | 0.76 | LOXL2 (0.42) | PDGFRBMKNK1MKNK2 | |
| SCHEMBL14736598 | 0.76 | MAPT (0.52) | PDGFRBKITKDRADORA2A | |
| SCHEMBL8657051 | 0.75 | HSP90AA1 (0.41) | TLR8TAAR1DCUN1D1ATP4AATP4B | |
| SCHEMBL17843990 | 0.75 | MKNK1 (0.53) | PDGFRBKITKDRTLR8MKNK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0680967-B1 | Erythromycin derivatives, their process of preparation and their use as medicaments | HOECHST MARION ROUSSEL INC (FR) | 1998-10-14 | — | — | EP | claimed |