Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.53 |
| ▸ | LMNA | P02545 | 7/20 | 0.53 |
| ▸ | MEN1 | O00255 | 5/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | HTT | P42858 | 3/20 | 0.53 |
| ▸ | USP2 | O75604 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.42 |
| ▸ | FTO | Q9C0B1 | 4/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.42 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 2/20 | 0.42 |
| ▸ | BLM | P54132 | 2/20 | 0.42 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1024927 | 0.88 | MAPT (0.66) | MAPTLMNAMEN1KMT2AHTT | |
| SCHEMBL29349570 | 0.88 | MAPT (0.66) | MAPTLMNAMEN1KMT2AHTT | |
| SCHEMBL10145450 | 0.82 | MAPT (0.58) | MAPTLMNAMEN1KMT2AHTT | |
| SCHEMBL10101817 | 0.82 | MAPT (0.49) | MAPTLMNAMEN1KMT2AHTT | |
| SCHEMBL18184153 | 0.80 | MAPT (0.58) | MAPTLMNAMEN1KMT2AHTT | |
| SCHEMBL10101643 | 0.79 | MAPT (0.47) | MAPTLMNAMEN1KMT2AHTT | |
| SCHEMBL10100273 | 0.78 | MAPT (0.53) | MAPTLMNAMEN1KMT2AHTT | |
| SCHEMBL14005748 | 0.78 | MAPT (0.54) | MAPTLMNAMEN1KMT2AHTT | |
| SCHEMBL18184154 | 0.78 | MAPT (0.55) | MAPTLMNAMEN1KMT2AHTT | |
| SCHEMBL13914140 | 0.77 | MAPT (0.67) | MAPTLMNAMEN1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8173698-B2 | Fluorescent probes; solid phase synthesis; kits | Life Technologies Corporation (US) | 2012-05-08 | — | — | US | disclosed |
| US-20080160627-A1 | Environmental Sensitive Fluorogenic Compounds and Their Application for Singlet Oxygen and Protein Detection | INVITROGEN CORPORATION (US) | 2008-07-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080160627-A1 | Environmental Sensitive Fluorogenic Compounds and Their Application for Singlet Oxygen and Protein Detection | PPOX, HSPE1, PRDX3 | MAPT 1442/4885LMNA 2531/4885MEN1 4561/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.