SCHEMBL10100324

SCHEMBL10100324

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nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.33
TDP1 Q9NUW8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19443306 1.00 TSHR (0.33) TSHRTDP1
SCHEMBL223185 0.90 TSHR (0.33) TSHRTDP1
SCHEMBL15426520 0.86 TSHR (0.39) TSHRTDP1
SCHEMBL17945416 0.86 TSHR (0.39) TSHRTDP1
SCHEMBL325804 0.83 TSHR (0.40) TSHRTDP1
SCHEMBL224194 0.81
SCHEMBL1830689 0.81 TSHR (0.35) TSHRTDP1
SCHEMBL10100320 0.81
SCHEMBL15628682 0.80 TSHR (0.38) TSHRTDP1
SCHEMBL13877207 0.80 TSHR (0.38) TSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2114980-B1 ANTIVIRAL NUCLEOSIDE ANALOGS BIOCRYST PHARM INC (US) 2012-06-27 EP disclosed