SCHEMBL1830689

SCHEMBL1830689

CCC(C)OC(CO)CO

nearest known ligand 0.35

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.35
TDP1 Q9NUW8 1/20 0.33
MAPT P10636 1/20 0.30
MAPK1 P28482 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL223185 0.92 TSHR (0.33) TSHRTDP1
SCHEMBL24548365 0.85
SCHEMBL1830189 0.84 TDP1 (0.31) TDP1
SCHEMBL17945416 0.82 TSHR (0.39) TSHRTDP1MAPK1
SCHEMBL15426520 0.82 TSHR (0.39) TSHRTDP1MAPK1
SCHEMBL19443306 0.81 TSHR (0.33) TSHRTDP1
SCHEMBL10100324 0.81 TSHR (0.33) TSHRTDP1
SCHEMBL13254103 0.80
SCHEMBL13998564 0.80 TSHR (0.37) TSHRTDP1MAPK1
SCHEMBL224938 0.80

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8829229-B2 Polyol ethers and process for making them DOW GLOBAL TECHNOLOGIES LLC (US) 2014-09-09 US disclosed
EP-2318346-B1 POLYOL ETHERS AND PROCESS FOR MAKING THEM DOW GLOBAL TECHNOLOGIES LLC (US) 2013-11-20 EP disclosed
US-8329818-B2 Modified ethylene-vinyl alcohol copolymer and method for the production thereof KURARAY CO., LTD. (JP) 2012-12-11 US disclosed
EP-2318346-A1 POLYOL ETHERS AND PROCESS FOR MAKING THEM Dow Global Technologies LLC (US) 2011-05-11 EP disclosed
US-20100280178-A1 MODIFIED ETHYLENE-VINYL ALCOHOL COPOLYMER AND METHOD FOR THE PRODUCTION THEREOF KURARAY CO., LTD. (JP) 2010-11-04 US disclosed
US-7811646-B2 Modified ethylene-vinyl alcohol copolymer and method for the production thereof KURARAY CO., LTD. (JP) 2010-10-12 US disclosed
EP-1236511-B1 PROCESS FOR PRODUCING ETHER USING A PALALDIUM CATALYST KAO CORP (JP) 2010-06-09 EP disclosed
WO-2010027663-A1 POLYOL ETHERS AND PROCESS FOR MAKING THEM DOW GLOBAL TECHNOLOGIES INC. (US) 2010-03-11 WO disclosed
US-20100048940-A1 reductive etherification of a polyol with an aldehyde or ketone using a hydrogenation catalyt; resulting compounds have use as solvents, surfactants, degreasers, wetting agents, emulsifying agents, lubricants, and intermediates for surfactants; polyols can be from renewable raw materials DOW GLOBAL TECHNOLOGIES LLC 2010-02-25 US disclosed
US-7534829-B2 Resin composition and multi-layer structures KURARAY CO., LTD. (JP) 2009-05-19 US disclosed
US-6657089-B1 Reacting cyclic acetal containing hydroxy group with hydrogen in presence of palladium catalyst supported on mesoporous alumninosilicate; hydrogenation, decyclization, catalysis KAO CORPORATION (JP) 2003-12-02 US disclosed
EP-1236511-A1 PALLADIUM CATALYST AND PROCESS FOR PRODUCING ETHER Kao Corporation (JP) 2002-09-04 EP disclosed
CN-1219953-A Fabric softening compound/composition PROCTER & GAMBLE (US) 1999-06-16 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100048940-A1 reductive etherification of a polyol with an aldehyde or ketone using a hydrogenation catalyt; resulting compounds have use as solvents, surfactants, degreasers, wetting agents, emulsifying agents, lubricants, and intermediates for surfactants; polyols can be from renewable raw materials RNF114, USP14, USP13 TSHR 3945/4885TDP1 1846/4885MAPT 3513/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.