⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9912348 | 0.79 | DOT1L (0.30) | — | |
| SCHEMBL11924463 | 0.79 | DOT1L (0.30) | — | |
| SCHEMBL14140990 | 0.79 | — | — | |
| SCHEMBL15682803 | 0.77 | POLRMT (0.39) | — | |
| SCHEMBL13532237 | 0.77 | — | — | |
| SCHEMBL15682807 | 0.75 | POLRMT (0.30) | — | |
| SCHEMBL10143786 | 0.72 | — | — | |
| SCHEMBL10142421 | 0.72 | — | — | |
| SCHEMBL9912333 | 0.71 | — | — | |
| SCHEMBL13667813 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2114980-B1 | ANTIVIRAL NUCLEOSIDE ANALOGS | BIOCRYST PHARM INC (US) | 2012-06-27 | — | — | EP | disclosed |