SCHEMBL10100512

SCHEMBL10100512

O=C1c2ccc3c4c(ccc(c24)C(=O)N1N1CCCCC1)C(=O)N(N1CCCCC1)C3=O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TERT O14746 2/20 0.46
ALDH1A1 P00352 7/20 0.38
LMNA P02545 4/20 0.38
KDM4E B2RXH2 3/20 0.38
HPGD P15428 2/20 0.38
CYP1A2 P05177 1/20 0.38
CYP3A4 P08684 1/20 0.38
CYP2C9 P11712 1/20 0.38
HTT P42858 5/20 0.36
XBP1 P17861 1/20 0.36
HIF1A Q16665 1/20 0.36
MEN1 O00255 8/20 0.36
KMT2A Q03164 8/20 0.36
L3MBTL1 Q9Y468 5/20 0.36
MAPT P10636 4/20 0.36
RAB9A P51151 3/20 0.36
MAPK1 P28482 2/20 0.36
NPC1 O15118 2/20 0.36
AVPR1A P37288 1/20 0.36
POLB P06746 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13929460 0.89 PARP1 (0.40) TERTALDH1A1LMNAKDM4EHPGD
SCHEMBL11948126 0.88 ALDH1A1 (0.41) TERTALDH1A1LMNAKDM4EHPGD
SCHEMBL11948128 0.85 ALDH1A1 (0.50) ALDH1A1LMNAKDM4EHPGDCYP1A2
SCHEMBL28302109 0.84 ALDH1A1 (0.55) ALDH1A1LMNAKDM4EHPGDCYP1A2
SCHEMBL83222 0.83 ALDH1A1 (0.49) ALDH1A1HPGDCYP3A4CYP2C9HTT
SCHEMBL6193007 0.83 ALDH1A1 (0.49) ALDH1A1HPGDCYP3A4CYP2C9HTT
SCHEMBL29643230 0.83 ALDH1A1 (0.49) ALDH1A1HPGDCYP3A4CYP2C9HTT
SCHEMBL28420408 0.82 ERCC1 (0.55) ALDH1A1LMNAKDM4EHPGDCYP1A2
SCHEMBL13780638 0.81 MAPK1 (0.38) TERTALDH1A1LMNAKDM4EHPGD
SCHEMBL1001751 0.80 POLB (0.50) ALDH1A1HPGDHTTKMT2AL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8380109-B2 Image forming apparatus and process cartridge RICOH COMPANY, LTD. (JP) 2013-02-19 US disclosed
US-8380109-B2 Image forming apparatus and process cartridge RICOH COMPANY, LTD. (JP) 2013-02-19 US disclosed
US-8110326-B2 Electrophotographic photoreceptor, image forming apparatus, and process cartridge RICOH COMPANY LIMITED (JP) 2012-02-07 US disclosed
US-8110326-B2 Electrophotographic photoreceptor, image forming apparatus, and process cartridge RICOH COMPANY LIMITED (JP) 2012-02-07 US disclosed
US-20090180804-A1 Image forming apparatus and process cartridge RICOH COMPANY, LTD. 2009-07-16 US disclosed
US-20090180804-A1 Image forming apparatus and process cartridge RICOH COMPANY, LTD. 2009-07-16 US disclosed
US-20080298840-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, IMAGE FORMING APPARATUS, AND PROCESS CARTRIDGE RICOH COMPANY LIMITED (JP) 2008-12-04 US disclosed
US-20080298840-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, IMAGE FORMING APPARATUS, AND PROCESS CARTRIDGE RICOH COMPANY LIMITED (JP) 2008-12-04 US disclosed