SCHEMBL10100810

SCHEMBL10100810

Cc1cc(-n2c3ccccc3c3ccccc32)ccc1-c1c(C)cc(-n2c3ccccc3c3ccccc32)cc1C

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.46
ATM Q13315 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
LMNA P02545 4/20 0.36
ALDH1A1 P00352 2/20 0.36
POLB P06746 2/20 0.36
GPR3 P46089 1/20 0.35
ALKBH5 Q6P6C2 1/20 0.35
FTO Q9C0B1 1/20 0.35
NQO2 P16083 1/20 0.34
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
MAPT P10636 2/20 0.33
HTT P42858 1/20 0.33
NTRK1 P04629 1/20 0.32
HSP90AA1 P07900 1/20 0.32
IDO1 P14902 1/20 0.32
TP53 P04637 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.31
EDNRB P24530 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29349946 0.90 KDM4E (0.52) KDM4EATML3MBTL1LMNAALDH1A1
SCHEMBL29462706 0.90 KDM4E (0.52) KDM4EATML3MBTL1LMNAALDH1A1
SCHEMBL63587 0.90 KDM4E (0.52) KDM4EATML3MBTL1LMNAALDH1A1
SCHEMBL13049632 0.86 KDM4E (0.48) KDM4EATML3MBTL1LMNAALDH1A1
SCHEMBL10100831 0.86 KDM4E (0.48) KDM4EATML3MBTL1LMNAALDH1A1
SCHEMBL12888018 0.86 KDM4E (0.56) KDM4EATML3MBTL1LMNAALDH1A1
SCHEMBL14407567 0.85 KDM4E (0.44) KDM4EATML3MBTL1LMNAALDH1A1
SCHEMBL22062923 0.85 KDM4E (0.47) KDM4EATML3MBTL1LMNAALDH1A1
SCHEMBL7605746 0.84 KDM4E (0.44) KDM4EATML3MBTL1LMNAALDH1A1
SCHEMBL21037876 0.83 L3MBTL1 (0.50) KDM4EATML3MBTL1LMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8178214-B2 Material for organic electroluminescence element, organic electroluminescence element, display device and illumination device KONICA MINOLTA HOLDINGS, INC. (JP) 2012-05-15 US disclosed
US-8178214-B2 Material for organic electroluminescence element, organic electroluminescence element, display device and illumination device KONICA MINOLTA HOLDINGS, INC. (JP) 2012-05-15 US disclosed
US-20070184301-A1 Material for organic electroluminescence element, organic electroluminescence element, display device and illumination device KONICA MINOLTA HOLDINGS, INC. (JP) 2007-08-09 US disclosed
US-20070184301-A1 Material for organic electroluminescence element, organic electroluminescence element, display device and illumination device KONICA MINOLTA HOLDINGS, INC. (JP) 2007-08-09 US disclosed