SCHEMBL10100823

SCHEMBL10100823

Cc1cc(C)c(-c2ccc(-n3c4ccccc4c4ccccc43)cc2)c(C)c1-c1ccc(-n2c3ccccc3c3ccccc32)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.50
ATM Q13315 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
KMT2A Q03164 1/20 0.39
HDAC4 P56524 1/20 0.38
GPR3 P46089 1/20 0.35
ALKBH5 Q6P6C2 1/20 0.35
FTO Q9C0B1 1/20 0.35
AKR1C4 P17516 1/20 0.35
AKR1C3 P42330 1/20 0.35
AKR1C2 P52895 1/20 0.35
AKR1C1 Q04828 1/20 0.35
POLB P06746 1/20 0.34
NQO2 P16083 1/20 0.34
MAPK14 Q16539 2/20 0.34
EDNRA P25101 2/20 0.34
PTPN1 P18031 2/20 0.33
EDNRB P24530 1/20 0.33
MYC P01106 1/20 0.33
MAPK8 P45983 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13400015 0.90 L3MBTL1 (0.57) KDM4EATML3MBTL1KMT2AHDAC4
SCHEMBL10100808 0.88 KDM4E (0.52) KDM4EATML3MBTL1KMT2AHDAC4
SCHEMBL10100818 0.86 L3MBTL1 (0.57) KDM4EATML3MBTL1KMT2AHDAC4
SCHEMBL13776809 0.85 L3MBTL1 (0.48) KDM4EATML3MBTL1KMT2AHDAC4
SCHEMBL13382377 0.84 L3MBTL1 (0.44) KDM4EATML3MBTL1KMT2AHDAC4
SCHEMBL9890863 0.83 L3MBTL1 (0.53) KDM4EATML3MBTL1KMT2AHDAC4
SCHEMBL7603776 0.82 L3MBTL1 (0.53) KDM4EATML3MBTL1KMT2AHDAC4
SCHEMBL18406160 0.81 KDM4E (0.44) KDM4EATML3MBTL1KMT2AHDAC4
SCHEMBL12128018 0.81 KDM4E (0.52) KDM4EATML3MBTL1KMT2AHDAC4
SCHEMBL9890947 0.81 KDM4E (0.47) KDM4EATML3MBTL1KMT2AHDAC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8178214-B2 Material for organic electroluminescence element, organic electroluminescence element, display device and illumination device KONICA MINOLTA HOLDINGS, INC. (JP) 2012-05-15 US disclosed
US-8178214-B2 Material for organic electroluminescence element, organic electroluminescence element, display device and illumination device KONICA MINOLTA HOLDINGS, INC. (JP) 2012-05-15 US disclosed
US-7629060-B2 Liquid crystal cells; durability, stability; brightness ; containing carbazole compound KONICA MINOLTA HOLDINGS, INC. (JP) 2009-12-08 US disclosed
US-7629060-B2 Liquid crystal cells; durability, stability; brightness ; containing carbazole compound KONICA MINOLTA HOLDINGS, INC. (JP) 2009-12-08 US disclosed
US-20070184301-A1 Material for organic electroluminescence element, organic electroluminescence element, display device and illumination device KONICA MINOLTA HOLDINGS, INC. (JP) 2007-08-09 US disclosed
US-20070184301-A1 Material for organic electroluminescence element, organic electroluminescence element, display device and illumination device KONICA MINOLTA HOLDINGS, INC. (JP) 2007-08-09 US disclosed