SCHEMBL10101148

SCHEMBL10101148

CCC(=O)NCCCNC(=O)CC

nearest known ligand 0.89

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.89
KMT2A Q03164 1/20 0.89
RECQL P46063 1/20 0.52
CASP2 P42575 1/20 0.50
ALDH1A1 P00352 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
NAAA Q02083 1/20 0.46
EPHX1 P07099 2/20 0.44
KDM4E B2RXH2 1/20 0.43
MAPK1 P28482 1/20 0.43
HIF1A Q16665 1/20 0.43
FAAH O00519 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17229157 0.94 MEN1 (1.00) MEN1KMT2ARECQLCASP2ALDH1A1
SCHEMBL11758762 0.92 MEN1 (0.94) MEN1KMT2ARECQLCASP2ALDH1A1
SCHEMBL21765846 0.92 MEN1 (0.94) MEN1KMT2ARECQLCASP2ALDH1A1
SCHEMBL9259257 0.92 MEN1 (0.94) MEN1KMT2ARECQLCASP2ALDH1A1
SCHEMBL13024411 0.90 MEN1 (0.73) MEN1KMT2ARECQLCASP2ALDH1A1
SCHEMBL30941449 0.90 MEN1 (0.73) MEN1KMT2ARECQLCASP2ALDH1A1
SCHEMBL14439572 0.90 MEN1 (0.81) MEN1KMT2ARECQLCASP2ALDH1A1
SCHEMBL15934269 0.90 MEN1 (0.73) MEN1KMT2ARECQLCASP2ALDH1A1
SCHEMBL277343 0.89
SCHEMBL13492955 0.88 MEN1 (0.70) MEN1KMT2ARECQLCASP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0192299-B1 PROCESS FOR THE PREPARATION OF PYRIMIDINE AND 2-ALKYLPYRIMIDINE STAMICARBON B.V. (NL) 1990-08-29 EP claimed
US-4775755-A DIAMINOPROPANE OR TETRAHYDROPYRIMIDINE REACTED WITH FORMAMIDE STAMICARBON B. V. (NL) 1988-10-04 US claimed
EP-0192299-A1 Process for the preparation of pyrimidine and 2-alkylpyrimidine STAMICARBON B.V. (NL) 1986-08-27 EP claimed
EP-4212180-A1 MODIFIED THERAPEUTIC AGENTS, STAPLED PEPTIDE LIPID CONJUGATES, AND COMPOSITIONS THEREOF The Scripps Research Institute (US) 2023-07-19 EP disclosed
US-20210102185-A1 Protein Macrocyclization STICHTING VU (NL) 2021-04-08 US disclosed
US-9145514-B2 Temperature management indicator and structure having the same attached NICHIYU GIKEN KOGYO CO., LTD. (JP) 2015-09-29 US disclosed
US-9074264-B2 Method for recovering precious metal from solution containing precious metal ions, extracting agent or adsorbent used therefor, and back-extracting agent or desorbent TOSOH CORPORATION (JP) 2015-07-07 US disclosed
WO-2015095406-A1 MODIFIED THERAPEUTIC AGENTS, STAPLED PEPTIDE LIPID CONJUGATES, AND COMPOSITIONS THEREOF THE CALIFORNIA INSTITUTE FOR BIOMEDICAL RESEARCH (US) 2015-06-25 WO disclosed
US-20130281726-A1 METHOD FOR RECOVERING PRECIOUS METAL FROM SOLUTION CONTAINING PRECIOUS METAL IONS, EXTRACTING AGENT OR ADSORBENT USED THEREFOR, AND BACK-EXTRACTING AGENT OR DESORBENT TOSOH CORPORATION (JP) 2013-10-24 US disclosed
EP-2554961-A1 TEMPERATURE MANAGEMENT INDICATOR AND STRUCTURE HAVING THE SAME ATTACHED Nichiyu Giken Kogyo Co. Ltd. (JP) 2013-02-06 EP disclosed
US-20130014690-A1 TEMPERATURE MANAGEMENT INDICATOR AND STRUCTURE HAVING THE SAME ATTACHED NICHIYU GIKEN KOGYO CO., LTD. (JP) 2013-01-17 US disclosed
US-20120164039-A1 PALLADIUM ION ADSORBENT AND METHODS FOR SEPARATING AND RECOVERING PALLADIUM USING IT TOSOH CORPORATION (JP) 2012-06-28 US disclosed
EP-0192299-B1 PROCESS FOR THE PREPARATION OF PYRIMIDINE AND 2-ALKYLPYRIMIDINE STAMICARBON B.V. (NL) 1990-08-29 EP disclosed
US-4775755-A DIAMINOPROPANE OR TETRAHYDROPYRIMIDINE REACTED WITH FORMAMIDE STAMICARBON B. V. (NL) 1988-10-04 US disclosed
US-4775755-A DIAMINOPROPANE OR TETRAHYDROPYRIMIDINE REACTED WITH FORMAMIDE STAMICARBON B. V. (NL) 1988-10-04 US disclosed
EP-0192299-A1 Process for the preparation of pyrimidine and 2-alkylpyrimidine STAMICARBON B.V. (NL) 1986-08-27 EP disclosed
EP-0192299-A1 Process for the preparation of pyrimidine and 2-alkylpyrimidine STAMICARBON B.V. (NL) 1986-08-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120164039-A1 PALLADIUM ION ADSORBENT AND METHODS FOR SEPARATING AND RECOVERING PALLADIUM USING IT PDCD10, PARK7, CCR10 MEN1 1969/4885KMT2A 643/4885RECQL 3794/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.