PARK7

Parkinson disease protein 7 · Q99497 · PARK7 on Sugi Atlas →

3,152 patent compounds predicted against PARK7, 1,652 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
SCHEMBL4785743 SCHEMBL4785743 1.00 10/20
SCHEMBL4784991 SCHEMBL4784991 0.81 7/20
SCHEMBL8040297 SCHEMBL8040297 0.68 7/20
SCHEMBL4784867 SCHEMBL4784867 0.82 6/20
SCHEMBL4786048 SCHEMBL4786048 0.78 6/20
SCHEMBL4785342 SCHEMBL4785342 0.72 6/20
SCHEMBL5126043 SCHEMBL5126043 0.60 6/20
SCHEMBL5362209 SCHEMBL5362209 0.48 6/20
Hydrochloric Acid Hydrochloric Acid (SCHEMBL5363890) 0.47 6/20
SCHEMBL4737404 SCHEMBL4737404 0.76 5/20
SCHEMBL5125074 SCHEMBL5125074 0.73 5/20
SCHEMBL9097463 SCHEMBL9097463 0.67 5/20
SCHEMBL7833229 SCHEMBL7833229 0.67 5/20
SCHEMBL2823268 SCHEMBL2823268 0.66 5/20
SCHEMBL4164986 SCHEMBL4164986 0.64 5/20
SCHEMBL4781749 SCHEMBL4781749 0.56 5/20
SCHEMBL5542403 SCHEMBL5542403 0.51 5/20
SCHEMBL2304183 SCHEMBL2304183 0.51 5/20
SCHEMBL4734272 SCHEMBL4734272 1.00 4/20
SCHEMBL4735921 SCHEMBL4735921 1.00 4/20

Clinical trials — most relevant to PARK7 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
A Study to Evaluate Efficacy, Safety and Tolerability of Hydroxychloroquine in Subjects With Parkinson's Disease PHASE2NOT_YET_RECRUITING
Mesenchymal Stem Cells Transplantation to Patients With Parkinson's Disease PHASE1/PHASE2UNKNOWN
Effects of Lithium Therapy on Blood-based Therapeutic Targets in Parkinson's Disease. PHASE1COMPLETED
A Clinical Study to Evaluate the Safety of MF1, a New Treatment for Parkinson's Disease-related Disorders (MF1 Study) PHASE1RECRUITING
Parkinson's Foundation PD GENEration Genetic Registry nanRECRUITING
Molecular Pathology and Neuronal Networks in LRRK2 Parkinson's Disease nanCOMPLETED
Combined Genome and RNA Sequencing for Genetic Diagnosis of Parkinsonism nanNOT_YET_RECRUITING
Genetic Characterization of Parkinson's Disease nanCOMPLETED
Parkinson's Families Project nanRECRUITING
PPMI Clinical - Establishing a Deeply Phenotyped PD Cohort nanRECRUITING
Parkinson's Repository of Biosamples and Network Datasets (Tracking Parkinson's) nanCOMPLETED
Rostock International Parkinson's Disease Study (ROPAD) nanCOMPLETED
The Differential Diagnosis and Prognosis of Idiopathic and Atypical Parkinson Disease by Using Diffusion MRI nanCOMPLETED
Parkinson's Research: The Organized Genetics Initiative nanCOMPLETED
PDGeneration: Mapping the Future of Parkinson's Disease nanUNKNOWN
Hereditary Parkinson s Disease Natural History Protocol nanCOMPLETED
Diagnosis of Parkinson´s Disease by Means of Submandibular Gland Needle Biopsy nanUNKNOWN
Gut Microbiota in the Progression of Alpha-synucleinopathies nanUNKNOWN
Genetic Analysis of Parkinson's Disease nanCOMPLETED
Assessing the Polygenic Burden of Rare Disruptive Mutations in Parkinson's Disease nanUNKNOWN
Unstructured Eye Tracking as a Diagnostic and Prognostic Biomarker in Parkinsonian Disorders nanUNKNOWN
Consortium On Risk for Early-onset Parkinson's Disease (CORE PD) nanCOMPLETED
Biomarkers of Risk of Parkinson Disease nanCOMPLETED
Striatal and Extra-Striatal Cholinergic Terminal Density in LRRK2-PD Mutation nanRECRUITING
Characterising Physiological Resilience in People With Parkinson's Disease nanNOT_YET_RECRUITING
Exercise Neuroprotection in Parkinson's Disease nanRECRUITING
Biomarker Analysis for GBA Associated Parkinson's Disease nanUNKNOWN
Genetics in Parkinson's Disease: Behavioral and Cognitive Outcomes nanRECRUITING
Toward Molecular Profiling of Parkinson's Disease in Easily Accessible Biological Matrices nanACTIVE_NOT_RECRUITING
The Personalized Parkinson Project (PPP) nanACTIVE_NOT_RECRUITING

Related proteins — ESM-2 sequence neighbours (a PARK7 binder may also engage these)

ProteinNameSimilarity
Q95LI9 1.000 Q95LI9 →
Q7TQ35 1.000 Q7TQ35 →
Q5E946 1.000 Q5E946 →
Q99LX0 1.000 Q99LX0 →
O88767 0.997 O88767 →
Q5XJ36 0.997 Q5XJ36 →
Q8UW59 0.991 Q8UW59 →
P21820 0.926 P21820 →
Q71R50 0.923 Q71R50 →
Q9BUP3 0.921 Q9BUP3 →
P12863 0.920 P12863 →
A1YFX9 0.920 A1YFX9 →
P48495 0.918 P48495 →
P48494 0.918 P48494 →
P48491 0.917 P48491 →
P40142 0.916 P40142 →
Q6B855 0.916 Q6B855 →
P34937 0.915 P34937 →
Q6P8M1 0.915 Q6P8M1 →
P46226 0.915 P46226 →
TKT Transketolase 0.914 landscape →
P17764 0.914 P17764 →
A2T7G9 0.914 A2T7G9 →
Q0II68 0.914 Q0II68 →
Q9WTL7 0.914 Q9WTL7 →
P50137 0.914 P50137 →
P48493 0.913 P48493 →
A1YER2 0.913 A1YER2 →
Q9QYL8 0.913 Q9QYL8 →
Q43199 0.913 Q43199 →