SCHEMBL10101154

SCHEMBL10101154

O=C1CSCC(=O)NCCNC(=O)CSCC(=O)NCCN1

nearest known ligand 0.42

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 3/20 0.42
OR51E2 Q9H255 1/20 0.41
GAA P10253 2/20 0.40
FKBP5 Q13451 1/20 0.39
GSK3A P49840 2/20 0.33
GSK3B P49841 2/20 0.33
MGAM O43451 1/20 0.33
SI P14410 1/20 0.33
MGAM2 Q2M2H8 1/20 0.33
MEN1 O00255 1/20 0.32
ALDH1A1 P00352 1/20 0.32
KMT2A Q03164 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8935767 0.92 CRBN (0.36) CRBNOR51E2GAAFKBP5
SCHEMBL9951175 0.88 OR51E2 (0.50) CRBNOR51E2GAAFKBP5GSK3A
SCHEMBL10083526 0.88 CRBN (0.55) CRBNOR51E2GAAFKBP5GSK3A
SCHEMBL9120251 0.83 GAA (0.31) CRBNOR51E2GAAFKBP5
SCHEMBL16212435 0.82
SCHEMBL89026 0.82
SCHEMBL10387267 0.82 GAA (0.48) CRBNOR51E2GAAFKBP5MEN1
Hydrochloric Acid SCHEMBL1524100 0.80
SCHEMBL1269125 0.78
SCHEMBL11556195 0.78 CRBN (0.35) CRBNOR51E2GAAFKBP5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120164039-A1 PALLADIUM ION ADSORBENT AND METHODS FOR SEPARATING AND RECOVERING PALLADIUM USING IT TOSOH CORPORATION (JP) 2012-06-28 US disclosed
US-20120164039-A1 PALLADIUM ION ADSORBENT AND METHODS FOR SEPARATING AND RECOVERING PALLADIUM USING IT TOSOH CORPORATION (JP) 2012-06-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120164039-A1 PALLADIUM ION ADSORBENT AND METHODS FOR SEPARATING AND RECOVERING PALLADIUM USING IT PDCD10, PARK7, CCR10 CRBN 955/4885OR51E2 165/4885GAA 4704/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.