⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10101485 | 0.87 | HIF1A (0.30) | — | |
| SCHEMBL10101484 | 0.83 | PDE4D (0.31) | — | |
| SCHEMBL646125 | 0.83 | ADORA2A (0.39) | — | |
| SCHEMBL10101469 | 0.82 | POLRMT (0.34) | — | |
| SCHEMBL19229336 | 0.80 | PDE4D (0.35) | — | |
| SCHEMBL19229287 | 0.80 | PDE4D (0.35) | — | |
| SCHEMBL18480778 | 0.80 | PDE4D (0.35) | — | |
| SCHEMBL18470926 | 0.80 | PDE4D (0.35) | — | |
| SCHEMBL19632930 | 0.79 | PDE4D (0.32) | — | |
| SCHEMBL19636526 | 0.79 | PDE4D (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8119607-B2 | Bicyclic nucleosides and nucleotides as therapeutic agents | BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) | 2012-02-21 | — | — | US | disclosed |
| US-20100035836-A1 | BICYCLIC NUCLEOSIDES AND NUCLEOTIDES AS THERAPEUTIC AGENTS | BIOTA SCIENTIFIC MANAGEMENT (AU) | 2010-02-11 | — | — | US | disclosed |