SCHEMBL10101920

SCHEMBL10101920

Cc1cc(N(C)C)nc(Nc2ccc3[nH]c(=O)[nH]c3c2)c1/N=N/c1c(C#N)cnn1-c1ncccn1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.37
MAPT P10636 2/20 0.37
TSHR P16473 2/20 0.37
CASP1 P29466 2/20 0.37
KMT2A Q03164 2/20 0.37
POLB P06746 1/20 0.37
HBB P68871 1/20 0.37
JAK1 P23458 3/20 0.36
JAK3 P52333 3/20 0.36
USP2 O75604 1/20 0.34
TP53 P04637 1/20 0.34
XBP1 P17861 1/20 0.34
RAB9A P51151 1/20 0.34
CASP7 P55210 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
BCL6 P41182 2/20 0.33
BCOR Q6W2J9 1/20 0.33
JAK2 O60674 1/20 0.32
SYK P43405 1/20 0.32
GRM4 Q14833 3/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10101996 0.82 MEN1 (0.37) MEN1MAPTTSHRCASP1KMT2A
SCHEMBL10101949 0.81 NPC1 (0.32) RAB9ASMN1; SMN2
SCHEMBL10101941 0.79 MEN1 (0.38) MEN1MAPTTSHRCASP1KMT2A
SCHEMBL10101991 0.79 JAK2 (0.40) MEN1MAPTTSHRCASP1KMT2A
SCHEMBL10101980 0.79 JAK2 (0.40) MEN1MAPTTSHRCASP1KMT2A
SCHEMBL10101931 0.79 MEN1 (0.35) MEN1MAPTTSHRCASP1KMT2A
SCHEMBL10106456 0.75 RAB9A (0.44) MEN1MAPTTSHRCASP1KMT2A
SCHEMBL10101919 0.73 NPC1 (0.34) MEN1TSHRKMT2ARAB9ASMN1; SMN2
SCHEMBL2743045 0.72 MAPT (0.44) MEN1MAPTKMT2APOLBRAB9A
SCHEMBL10106461 0.72 RAB9A (0.44) MEN1MAPTTSHRCASP1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8206465-B2 Azo pigments, pigment dispersion, coloring composition, and ink for inkjet recording FUJIFILM CORPORATION (JP) 2012-06-26 US disclosed
US-8206465-B2 Azo pigments, pigment dispersion, coloring composition, and ink for inkjet recording FUJIFILM CORPORATION (JP) 2012-06-26 US disclosed
US-20110011306-A1 AZO PIGMENTS, PIGMENT DISPERSION, COLORING COMPOSITION, AND INK FOR INKJET RECORDING FUJIFILM CORPORATION (JP) 2011-01-20 US disclosed
US-20110011306-A1 AZO PIGMENTS, PIGMENT DISPERSION, COLORING COMPOSITION, AND INK FOR INKJET RECORDING FUJIFILM CORPORATION (JP) 2011-01-20 US disclosed
EP-2253674-A1 AZO PIGMENT, PIGMENT DISPERSION, COLORING COMPOSITION, AND INKJET RECORDING INK FUJIFILM Corporation (JP) 2010-11-24 EP disclosed