SCHEMBL10102034

SCHEMBL10102034

CNc1nc(Nc2ccccn2)c(C(N)=O)c(C)c1/N=N/c1c(C#N)cnn1-c1ncccn1

nearest known ligand 0.35

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
USP7 Q93009 1/20 0.35
GRM5 P41594 1/20 0.33
JAK2 O60674 5/20 0.32
JAK1 P23458 5/20 0.32
TYK2 P29597 2/20 0.32
BTK Q06187 1/20 0.32
JAK3 P52333 3/20 0.31
KCNH2 Q12809 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10102015 0.87 KDR (0.31)
SCHEMBL10102047 0.87 CSNK2A1 (0.32)
SCHEMBL10102012 0.80 CDK2 (0.35) USP7JAK2KCNH2
SCHEMBL10102041 0.77 ALDH1A1 (0.38)
SCHEMBL10102105 0.77 ALDH1A1 (0.38)
SCHEMBL10102026 0.76 MAP2K1 (0.36)
SCHEMBL10102025 0.76 HSD17B10 (0.36)
SCHEMBL10102001 0.75 CSNK2A1 (0.35)
SCHEMBL10102018 0.75 ALDH1A1 (0.31)
SCHEMBL10102014 0.75 MAPT (0.37)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8206465-B2 Azo pigments, pigment dispersion, coloring composition, and ink for inkjet recording FUJIFILM CORPORATION (JP) 2012-06-26 US disclosed
US-8206465-B2 Azo pigments, pigment dispersion, coloring composition, and ink for inkjet recording FUJIFILM CORPORATION (JP) 2012-06-26 US disclosed
US-20110011306-A1 AZO PIGMENTS, PIGMENT DISPERSION, COLORING COMPOSITION, AND INK FOR INKJET RECORDING FUJIFILM CORPORATION (JP) 2011-01-20 US disclosed
US-20110011306-A1 AZO PIGMENTS, PIGMENT DISPERSION, COLORING COMPOSITION, AND INK FOR INKJET RECORDING FUJIFILM CORPORATION (JP) 2011-01-20 US disclosed
EP-2253674-A1 AZO PIGMENT, PIGMENT DISPERSION, COLORING COMPOSITION, AND INKJET RECORDING INK FUJIFILM Corporation (JP) 2010-11-24 EP disclosed