SCHEMBL10102076

SCHEMBL10102076

COCCCNc1cc(C)cc(NCCCOC)n1

nearest known ligand 0.46

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.46
HTT P42858 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
DYRK1A Q13627 1/20 0.44
KCNH3 Q9ULD8 1/20 0.43
KDM4E B2RXH2 7/20 0.40
POLB P06746 3/20 0.40
PIM1 P11309 1/20 0.40
PIM2 Q9P1W9 1/20 0.40
TLR8 Q9NR97 1/20 0.40
MAPT P10636 1/20 0.40
HPGD P15428 1/20 0.40
TSHR P16473 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
ALDH1A1 P00352 4/20 0.38
PKM P14618 1/20 0.38
GAA P10253 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13989429 0.86 TLR8 (0.50) LMNAHTTSMN1; SMN2TLR8MAPT
SCHEMBL14004142 0.83 KDM4E (0.39) LMNAHTTSMN1; SMN2DYRK1AKDM4E
SCHEMBL13989398 0.82 SMN1; SMN2 (0.48) LMNAHTTSMN1; SMN2KDM4EPOLB
SCHEMBL14004140 0.82 KDM4E (0.38) LMNAHTTSMN1; SMN2DYRK1AKDM4E
SCHEMBL14004141 0.80 KDM4E (0.37) LMNAHTTSMN1; SMN2DYRK1AKDM4E
SCHEMBL8277611 0.80 SMN1; SMN2 (0.51) LMNAHTTSMN1; SMN2POLBALDH1A1
SCHEMBL13116015 0.79 CDC7 (0.47) HTTSMN1; SMN2KCNH3KDM4EPOLB
SCHEMBL13989410 0.79 TLR8 (0.61) LMNAHTTSMN1; SMN2TLR8MAPT
SCHEMBL14004164 0.78 KDM4E (0.36) LMNAHTTSMN1; SMN2DYRK1AKDM4E
SCHEMBL10692899 0.76 ESR1 (0.41) LMNAHTTSMN1; SMN2DYRK1AKCNH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8206465-B2 Azo pigments, pigment dispersion, coloring composition, and ink for inkjet recording FUJIFILM CORPORATION (JP) 2012-06-26 US disclosed
US-8206465-B2 Azo pigments, pigment dispersion, coloring composition, and ink for inkjet recording FUJIFILM CORPORATION (JP) 2012-06-26 US disclosed
US-20110011306-A1 AZO PIGMENTS, PIGMENT DISPERSION, COLORING COMPOSITION, AND INK FOR INKJET RECORDING FUJIFILM CORPORATION (JP) 2011-01-20 US disclosed
US-20110011306-A1 AZO PIGMENTS, PIGMENT DISPERSION, COLORING COMPOSITION, AND INK FOR INKJET RECORDING FUJIFILM CORPORATION (JP) 2011-01-20 US disclosed