Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 5/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | DNM2 | P50570 | 8/20 | 0.45 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.41 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9313985 | 0.90 | TLR8 (0.65) | TLR8ALDH1A1LMNATP53TSHR | |
| SCHEMBL13989429 | 0.88 | TLR8 (0.50) | TLR8ALDH1A1LMNATP53TSHR | |
| SCHEMBL24672584 | 0.85 | TLR8 (0.58) | TLR8ALDH1A1LMNATP53TSHR | |
| SCHEMBL8543215 | 0.83 | DNM2 (0.57) | TLR8ALDH1A1LMNATP53TSHR | |
| SCHEMBL14004165 | 0.82 | TLR8 (0.44) | TLR8ALDH1A1LMNATP53TSHR | |
| SCHEMBL13989398 | 0.80 | SMN1; SMN2 (0.48) | TLR8ALDH1A1LMNATP53TSHR | |
| SCHEMBL10102076 | 0.79 | LMNA (0.46) | TLR8ALDH1A1LMNATSHRHTT | |
| SCHEMBL13989433 | 0.78 | SLC29A1 (0.48) | TLR8ALDH1A1LMNATP53TSHR | |
| SCHEMBL12963699 | 0.78 | NOS3 (0.55) | TLR8ALDH1A1LMNATP53TSHR | |
| SCHEMBL16608857 | 0.77 | ALDH1A1 (0.73) | TLR8ALDH1A1LMNATP53TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080312352-A1 | Dyes and Dye Mixtures for Dying Polymers, Method for the Production Thereof and Their Use | DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) | 2008-12-18 | — | — | US | disclosed |