Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 18/20 | 0.58 |
| ▸ | AGXT | P21549 | 10/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL662808 | 0.98 | IDO1 (0.59) | IDO1AGXTCYP3A4 | |
| SCHEMBL7889545 | 0.81 | MAOB (0.47) | — | |
| SCHEMBL25580256 | 0.81 | IDO1 (0.54) | IDO1AGXTCYP3A4 | |
| SCHEMBL1715798 | 0.81 | IDO1 (0.52) | IDO1AGXT | |
| SCHEMBL1520817 | 0.81 | IDO1 (0.68) | IDO1AGXTCYP3A4 | |
| Hydrochloric Acid SCHEMBL1714972 | 0.79 | IDO1 (0.53) | IDO1AGXT | |
| SCHEMBL4808098 | 0.79 | MAOB (0.46) | — | |
| SCHEMBL1716084 | 0.78 | IDO1 (0.67) | IDO1AGXT | |
| SCHEMBL12509342 | 0.77 | MAOB (0.49) | — | |
| SCHEMBL4799836 | 0.77 | MAOB (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8536157-B2 | Non-steroidal compounds | THE UNIVERSITY OF MELBOURNE (AU) | 2013-09-17 | — | — | US | disclosed |
| US-20120046255-A1 | NON-STEROIDAL COMPOUNDS | THE UNIVERSITY OF MELBOURNE of ROYAL PARADE PARKVILLE (AU) | 2012-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120046255-A1 | NON-STEROIDAL COMPOUNDS | PTGES2, PTGES, PTGES3 | IDO1 2049/4885AGXT 2786/4885CYP3A4 500/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.