Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 2/20 | 0.59 |
| ▸ | PPARG | P37231 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | DRD2 | P14416 | 1/20 | 0.54 |
| ▸ | DRD4 | P21917 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | PPARD | Q03181 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20230314 | 1.00 | PPARA (0.59) | PPARAPPARGKMT2ASMN1; SMN2KDM4E | |
| SCHEMBL13450150 | 1.00 | PPARA (0.59) | PPARAPPARGKMT2ASMN1; SMN2KDM4E | |
| SCHEMBL8357771 | 1.00 | PPARA (0.59) | PPARAPPARGKMT2ASMN1; SMN2KDM4E | |
| SCHEMBL8278944 | 0.98 | KMT2A (0.60) | PPARAPPARGKMT2ASMN1; SMN2KDM4E | |
| SCHEMBL826321 | 0.94 | SMN1; SMN2 (0.65) | KMT2ASMN1; SMN2KDM4EMAPK1HPGD | |
| SCHEMBL2777259 | 0.89 | L3MBTL1 (0.64) | KMT2ASMN1; SMN2KDM4EMAPK1HPGD | |
| SCHEMBL31302989 | 0.89 | L3MBTL1 (0.64) | KMT2ASMN1; SMN2KDM4EMAPK1HPGD | |
| SCHEMBL30639265 | 0.89 | PPARA (0.58) | PPARAFFAR4 | |
| SCHEMBL19246549 | 0.88 | KMT2A (0.58) | KMT2ASMN1; SMN2KDM4EMAPK1HPGD | |
| Hydrochloric Acid SCHEMBL2777750 | 0.87 | L3MBTL1 (0.62) | KMT2ASMN1; SMN2KDM4EMAPK1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018102693-A1 | CELL IMPERMEABLE COELENTERAZINE ANALOGUES | PROMEGA CORPORATION (US) | 2018-06-07 | — | — | WO | disclosed |
| EP-2409569-B1 | Method for administering GLP-1 molecules | EMISPHERE TECH INC (US) | 2017-08-16 | — | — | EP | disclosed |
| EP-2409569-A2 | Method for administering GLP-1 molecules | Emisphere Technologies, Inc. (US) | 2012-01-25 | — | — | EP | disclosed |