SCHEMBL1010368

SCHEMBL1010368

CC(=O)C(C)C(O)=S

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7856029 0.78
SCHEMBL93292 0.75
SCHEMBL7856027 0.75
SCHEMBL5386710 0.73
SCHEMBL79779 0.73
SCHEMBL9268689 0.73
SCHEMBL3118270 0.73
SCHEMBL8721593 0.73
SCHEMBL10640209 0.73
SCHEMBL18139663 0.73 TDP1 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 211 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024091979-A1 CD276 (B7-H3) ANTIBODY-DRUG CONJUGATES BRICKBIO, INC. (US) 2024-05-02 WO claimed
WO-2001040306-A9 HUMAN ANTIBODIES AS DETECTION REAGENTS BIOSITE DIAGNOSTICS INC (US) 2002-05-30 WO claimed
US-20250241872-A1 AFFINITY MEDICANT CONJUGATE Illudent, Inc. (US) 2025-07-31 US disclosed
WO-2024091979-A1 CD276 (B7-H3) ANTIBODY-DRUG CONJUGATES BRICKBIO, INC. (US) 2024-05-02 WO disclosed
EP-4347599-A1 SYNTHESIS OF BTK INHIBITOR AND INTERMEDIATES THEREOF Merck Sharp & Dohme LLC (US) 2024-04-10 EP disclosed
EP-4257186-A2 AFFINITY MEDICANT CONJUGATES AF Chemicals LLC (US) 2023-10-11 EP disclosed
EP-4251206-A1 PROTEIN DERIVATIVES CONTAINING UNNATURAL AMINO ACIDS AND BRANCHED LINKERS Brickbio, Inc. (US) 2023-10-04 EP disclosed
EP-3129357-B1 AFFINITY MEDICANT CONJUGATES AF CHEMICALS LLC (US) 2023-08-23 EP disclosed
EP-4210725-A1 ANTIBODIES CONTAINING UNNATURAL AMINO ACIDS AND METHODS OF MAKING AND USING THE SAME Brickbio, Inc. (US) 2023-07-19 EP disclosed
EP-4159795-A1 THERAPEUTIC CONJUGATES WITH SULFATED DENDRIMERS FOR INTRACELLULAR TARGETING ICD-Therapeutics GmbH (DE) 2023-04-05 EP disclosed
US-11576876-B2 Affinity Medicant Conjugate AF CHEMICALS, LLC (US) 2023-02-14 US disclosed
US-4689343-A AGRICULTURE BAYER AKTIENGESELLSCHAFT (DE) 1987-08-25 US disclosed
US-4684660-A Mercaptoacyldepeptides E. R. SQUIBB & SONS, INC. (US) 1987-08-04 US disclosed
US-4599350-A PHYTOPATHOGENS BAYER AKTIENGESELLSCHAFT (DE) 1986-07-08 US disclosed
EP-0144895-A2 Thiolan-2,4-dion-3-carboxamides BAYER AG (DE) 1985-06-19 EP disclosed
EP-0009898-B1 NOVEL ANTI-HYPERTENSIVE MERCAPTOACYLAMINO ACID DERIVATIVES, THEIR PREPARATION AND USE UNIVERSITY OF MIAMI (US) 1983-05-18 EP disclosed
EP-0078002-A2 Herbicides containing triazolo(2,3-b)quinazolone as active ingredient, and their use as plant growth regulators BASF Aktiengesellschaft (DE) 1983-05-04 EP disclosed
US-4322214-A USING A SULFUR OR SULFURIZED VAT DYE IN AN ALKALINE BATH CONTAINING A MERCAPTO COMPOUND AND A SULFITE SALT; LEVELING ASAHI CHEMICAL COMPANY LIMITED (JP) 1982-03-30 US disclosed
EP-0038117-A1 Methods for preparing anti-hypertensive agents UNIVERSITY OF MIAMI (US) 1981-10-21 EP disclosed
EP-0009898-A1 Novel anti-hypertensive mercaptoacylamino acid derivatives, their preparation and use UNIVERSITY OF MIAMI (US) 1980-04-16 EP disclosed