⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL177800 | 0.77 | — | — | |
| SCHEMBL1051612 | 0.75 | — | — | |
| SCHEMBL7856029 | 0.75 | — | — | |
| SCHEMBL7856027 | 0.73 | — | — | |
| Water SCHEMBL28020882 | 0.73 | TP53 (0.42) | — | |
| SCHEMBL1010368 | 0.73 | — | — | |
| SCHEMBL7767408 | 0.72 | SLC7A5 (0.36) | — | |
| SCHEMBL7767405 | 0.72 | SLC7A5 (0.36) | — | |
| SCHEMBL14615805 | 0.71 | LMNA (0.38) | — | |
| SCHEMBL6893128 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2104590-A | — | — | None | — | — | JP | disclosed |
| JP-55149245-A | — | — | None | — | — | JP | disclosed |
| US-5466708-A | Carbamyloxyoxetanone compounds | HOFFMANN-LA ROCHE INC. (US) | 1995-11-14 | — | — | US | disclosed |
| US-5376674-A | Lipase inhibitors | HOFFMAN-LA ROCHE INC. (US) | 1994-12-27 | — | — | US | disclosed |
| US-5260310-A | Oxetanone compounds and pharmaceutical compositions containing them | HOFFMANN-LA ROCHE INC. (US) | 1993-11-09 | — | — | US | disclosed |
| JP-H02104590-A | PRODUCTION OF ANTIBIOTIC | KIKUCHI TOYOHIKO | 1990-04-17 | — | — | JP | disclosed |
| JP-S55149245-A | PREPARATION OF 3-N-SUBSTITUTED CARBAMOYLTHIOPROPIONIC ACID DERIVATIVE | YOSHITOMI PHARMACEUT IND LTD | 1980-11-20 | — | — | JP | disclosed |