⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10104002 | 0.94 | — | — | |
| SCHEMBL10104298 | 0.94 | — | — | |
| SCHEMBL14606377 | 0.88 | HDAC8 (0.30) | — | |
| SCHEMBL13457826 | 0.88 | HDAC8 (0.30) | — | |
| SCHEMBL13043395 | 0.87 | — | — | |
| SCHEMBL14502803 | 0.86 | APP (0.30) | — | |
| SCHEMBL10104361 | 0.86 | ADRA2A (0.30) | — | |
| SCHEMBL18774346 | 0.86 | — | — | |
| SCHEMBL13069360 | 0.85 | MAPT (0.34) | — | |
| SCHEMBL13830274 | 0.85 | SMN1; SMN2 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2018847-B1 | Hair composition comprising at least one direct disulfide dye and at least one alkali hydroxide agent and method of simultaneous styling and dyeing. | ORÉAL L (FR) | 2014-09-17 | — | — | EP | disclosed |
| EP-2053094-B1 | Composition for dyeing keratinous fibres comprising at least one direct dye with disulphur/thiol function and at least one polymer with thiol function and method using the composition | OREAL (FR) | 2014-03-26 | — | — | EP | disclosed |
| US-8097044-B2 | Hair compositions comprising at least one disulfide direct dye and at least one alkaline hydroxide agent and simultaneous hair shaping and dyeing processes | L'OREAL S.A. (FR) | 2012-01-17 | — | — | US | disclosed |
| EP-2336248-A1 | Dying composition comprising a particular disulfide dye and process of dying keratinous fibres with this dye | L'Oréal (FR) | 2011-06-22 | — | — | EP | disclosed |
| EP-2333018-A1 | Dying composition comprising a particular disulfide dye and process of dying keratinous fibres with this dye | L'Oréal (FR) | 2011-06-15 | — | — | EP | disclosed |
| EP-2330160-A1 | Dying composition comprising a particular disulfide dye and process of dying keratinous fibres with this dye | L'Oréal (FR) | 2011-06-08 | — | — | EP | disclosed |
| EP-1647580-B1 | Dying composition comprising a particular disulfide dye and process of dying keratinous fibres with this dye. | OREAL (FR) | 2011-02-16 | — | — | EP | disclosed |
| WO-2009109457-A2 | COMPOSITION FOR DYEING KERATIN FIBRES COMPRISING AT LEAST ONE DIRECT DYE COMPRISING A DISULPHIDE/PROTECTED-THIOL FUNCTION AND AT LEAST ONE SILICEOUS COMPOUND COMPRISING A THIOL FUNCTION AND METHOD USING THE COMPOSITION | L'OREAL (FR) | 2009-09-11 | — | — | WO | disclosed |
| US-20090126755-A1 | Hair compositions comprising at least one disulfide direct dye and at least one alkaline hydroxide agent and simultaneous hair shaping an dyeing processes | L'OREAL S.A. (FR) | 2009-05-21 | — | — | US | disclosed |
| EP-2053094-A2 | Composition for dyeing keratinous fibres comprising at least one direct dye with disulphur/thiol function and at least one polymer with thiol function and method using the composition | L'Oréal (FR) | 2009-04-29 | — | — | EP | disclosed |
| US-7488354-B2 | Dyeing composition comprising at least one disulphide dye and method of dyeing human keratin fibers using this dye | L'OREAL S.A. (FR) | 2009-02-10 | — | — | US | disclosed |
| US-7488354-B2 | Dyeing composition comprising at least one disulphide dye and method of dyeing human keratin fibers using this dye | L'OREAL S.A. (FR) | 2009-02-10 | — | — | US | disclosed |
| EP-2018847-A1 | Hair composition comprising at least one direct disulfide dye and at least one alkali hydroxide agent and method of simultaneous styling and dyeing. | L'Oreal (FR) | 2009-01-28 | — | — | EP | disclosed |