Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4A | O75164 | 4/20 | 0.74 |
| ▸ | KDM2A | Q9Y2K7 | 4/20 | 0.74 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.72 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.72 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.72 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.72 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.72 |
| ▸ | INSR | P06213 | 3/20 | 0.60 |
| ▸ | CHAT | P28329 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | APAF1 | O14727 | 1/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10103994 | 1.00 | KDM4A (0.74) | KDM4AKDM2ACHRM2CHRM1CHRM4 | |
| SCHEMBL8725292 | 1.00 | KDM4A (0.74) | KDM4AKDM2ACHRM2CHRM1CHRM4 | |
| SCHEMBL8725304 | 1.00 | KDM4A (0.74) | KDM4AKDM2ACHRM2CHRM1CHRM4 | |
| SCHEMBL13924726 | 1.00 | KDM4A (0.74) | KDM4AKDM2ACHRM2CHRM1CHRM4 | |
| SCHEMBL13924760 | 1.00 | KDM4A (0.74) | KDM4AKDM2ACHRM2CHRM1CHRM4 | |
| Iodide SCHEMBL8723083 | 0.99 | KDM4A (0.74) | KDM4AKDM2ACHRM2CHRM1CHRM4 | |
| Iodide SCHEMBL8723080 | 0.99 | KDM4A (0.74) | KDM4AKDM2ACHRM2CHRM1CHRM4 | |
| SCHEMBL8727750 | 0.97 | KDM4A (0.74) | KDM4AKDM2ACHRM2CHRM1CHRM4 | |
| SCHEMBL8727754 | 0.97 | KDM4A (0.74) | KDM4AKDM2ACHRM2CHRM1CHRM4 | |
| Bromide SCHEMBL10845617 | 0.96 | KDM4A (0.72) | KDM4AKDM2ACHRM2CHRM1CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8097044-B2 | Hair compositions comprising at least one disulfide direct dye and at least one alkaline hydroxide agent and simultaneous hair shaping and dyeing processes | L'OREAL S.A. (FR) | 2012-01-17 | — | — | US | disclosed |
| US-20090126755-A1 | Hair compositions comprising at least one disulfide direct dye and at least one alkaline hydroxide agent and simultaneous hair shaping an dyeing processes | L'OREAL S.A. (FR) | 2009-05-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090126755-A1 | Hair compositions comprising at least one disulfide direct dye and at least one alkaline hydroxide agent and simultaneous hair shaping an dyeing processes | KRT18, DSG1, ALPG | KDM4A 626/4885KDM2A 690/4885CHRM2 4532/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.