Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 6/20 | 0.72 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.68 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.68 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.68 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.68 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.68 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.68 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.68 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.68 |
| ▸ | MEN1 | O00255 | 1/20 | 0.66 |
| ▸ | POLB | P06746 | 1/20 | 0.66 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.66 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.66 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.66 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.66 |
| ▸ | CHRNA10 | Q9GZZ6 | 5/20 | 0.56 |
| ▸ | CHRNA9 | Q9UGM1 | 5/20 | 0.56 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18999281 | 0.93 | CHRNA7 (0.64) | CHRNA7CYP3A4ALOX15CHRNB2NFKB1 | |
| SCHEMBL10105155 | 0.85 | CHRNA7 (0.63) | CHRNA7CYP3A4ALOX15CHRNB2NFKB1 | |
| SCHEMBL10115432 | 0.84 | CHRNA7 (1.00) | CHRNA7CYP3A4ALOX15CHRNB2NFKB1 | |
| SCHEMBL6744524 | 0.83 | CHRNA10 (0.56) | CHRNA7CYP3A4ALOX15CHRNB2NFKB1 | |
| Hydrochloric Acid SCHEMBL5350248 | 0.82 | CHRNA10 (0.55) | CHRNA7CYP3A4ALOX15CHRNB2NFKB1 | |
| Dimethylphenylpiperazinium SCHEMBL3453554 | 0.81 | CHRNA7 (1.00) | CHRNA7CYP3A4ALOX15CHRNB2NFKB1 | |
| Dimethylphenylpiperazinium SCHEMBL1427906 | 0.79 | CHRNA7 (0.96) | CHRNA7CYP3A4ALOX15CHRNB2NFKB1 | |
| Dimethylphenylpiperazinium SCHEMBL6829257 | 0.79 | CHRNA7 (0.96) | CHRNA7CYP3A4ALOX15CHRNB2NFKB1 | |
| Dimethylphenylpiperazinium SCHEMBL305083 | 0.79 | MEN1 (1.00) | CHRNA7CYP3A4ALOX15CHRNB2NFKB1 | |
| SCHEMBL10115489 | 0.78 | CHRNA7 (0.80) | CHRNA7CYP3A4ALOX15CHRNB2NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240359168-A1 | Mesoporous Catalyst Compounds and Uses Thereof | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY | 2024-10-31 | — | — | US | disclosed |
| US-12064752-B2 | Mesoporous catalyst compounds and uses thereof | ExxonMobil Technology and Engineering Company (US) | 2024-08-20 | — | — | US | disclosed |
| US-20220143586-A1 | Mesoporous Catalyst Compounds and Uses Thereof | EXXONMOBIL RES & ENG CO (US) | 2022-05-12 | — | — | US | disclosed |
| EP-3941621-A1 | MESOPOROUS CATALYST COMPOUNDS AND USES THEREOF | ExxonMobil Research and Engineering Company (US) | 2022-01-26 | — | — | EP | disclosed |
| WO-2020190367-A1 | MESOPOROUS CATALYST COMPOUNDS AND USES THEREOF | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2020-09-24 | — | — | WO | disclosed |
| EP-2920113-B1 | SYNTHESIS OF MCM-68 MOLECULAR SIEVE | EXXONMOBIL RES & ENG CO (US) | 2018-01-03 | — | — | EP | disclosed |
| US-9504995-B2 | Synthesis of MSE-framework type molecular sieves | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2016-11-29 | — | — | US | disclosed |
| US-20140140921-A1 | SYNTHESIS OF MSE-FRAMEWORK TYPE MOLECULAR SIEVES | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2014-05-22 | — | — | US | disclosed |
| US-8557804-B2 | Nicotinic receptor agonists for the treatment of inflammatory diseases | UNIVERSITE LAVAL (CA) | 2013-10-15 | — | — | US | disclosed |
| US-8557804-B2 | Nicotinic receptor agonists for the treatment of inflammatory diseases | UNIVERSITE LAVAL (CA) | 2013-10-15 | — | — | US | disclosed |
| US-8551983-B2 | Nicotinic receptor agonists for the treatment of inflammatory diseases | UNIVERSITE LAVAL (CA) | 2013-10-08 | — | — | US | disclosed |
| US-8551983-B2 | Nicotinic receptor agonists for the treatment of inflammatory diseases | UNIVERSITE LAVAL (CA) | 2013-10-08 | — | — | US | disclosed |
| US-20120022049-A1 | NICOTINIC RECEPTOR AGONISTS FOR THE TREATMENT OF INFLAMMATORY DISEASES | UNIVERSITE LAVAL (CA) | 2012-01-26 | — | — | US | disclosed |
| US-20120022049-A1 | NICOTINIC RECEPTOR AGONISTS FOR THE TREATMENT OF INFLAMMATORY DISEASES | UNIVERSITE LAVAL (CA) | 2012-01-26 | — | — | US | disclosed |
| US-8039459-B2 | especially dimethylphenylpiperazinium; treating a variety of pulmonary diseases with fewer side effects than other anti-inflammatory drugs, such as steroids | UNIVERSITE LAVAL (CA) | 2011-10-18 | — | — | US | disclosed |
| US-8039459-B2 | especially dimethylphenylpiperazinium; treating a variety of pulmonary diseases with fewer side effects than other anti-inflammatory drugs, such as steroids | UNIVERSITE LAVAL (CA) | 2011-10-18 | — | — | US | disclosed |
| US-20080221085-A1 | Nicotinic Receptor Agonists for the Treatment of Inflammatory Diseases | UNIVERSITE LAVAL (CA) | 2008-09-11 | — | — | US | disclosed |
| US-20080221085-A1 | Nicotinic Receptor Agonists for the Treatment of Inflammatory Diseases | UNIVERSITE LAVAL (CA) | 2008-09-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080221085-A1 | Nicotinic Receptor Agonists for the Treatment of Inflammatory Diseases | CHRNA1, CHRNG, CHRM1 | CHRNA7 6/4885CYP3A4 1085/4885ALOX15 982/4885 |
| US-20120022049-A1 | NICOTINIC RECEPTOR AGONISTS FOR THE TREATMENT OF INFLAMMATORY DISEASES | CHRNA1, CHRNG, CHRM1 | CHRNA7 6/4885CYP3A4 1085/4885ALOX15 982/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.