Dimethylphenylpiperazinium

Dimethylphenylpiperazinium

SCHEMBL3453554

C[N+]1(C)CCN(c2ccccc2)CC1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRNA7 P36544 3/20 1.00
CYP3A4 P08684 1/20 1.00
ALOX15 P16050 1/20 1.00
CHRNB2 P17787 1/20 1.00
NFKB1 P19838 1/20 1.00
MAPK1 P28482 1/20 1.00
CHRNA3 P32297 1/20 1.00
CHRNA4 P43681 1/20 1.00
HSD17B10 Q99714 1/20 1.00
MEN1 O00255 1/20 0.96
POLB P06746 1/20 0.96
APOBEC3A P31941 1/20 0.96
PMP22 Q01453 1/20 0.96
KMT2A Q03164 1/20 0.96
SMN1; SMN2 Q16637 1/20 0.96
HIF1A Q16665 1/20 0.96
APOBEC3G Q9HC16 1/20 0.96
HTR3E A5X5Y0 2/20 0.61
HTR3B O95264 2/20 0.61
HTR3A P46098 2/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dimethylphenylpiperazinium SCHEMBL1427906 0.98 CHRNA7 (0.96) CHRNA7CYP3A4ALOX15CHRNB2NFKB1
Dimethylphenylpiperazinium SCHEMBL6829257 0.98 CHRNA7 (0.96) CHRNA7CYP3A4ALOX15CHRNB2NFKB1
Dimethylphenylpiperazinium SCHEMBL305083 0.98 MEN1 (1.00) CHRNA7CYP3A4ALOX15CHRNB2NFKB1
SCHEMBL10114942 0.92 CHRNA7 (0.85) CHRNA7CYP3A4ALOX15CHRNB2NFKB1
Iodide SCHEMBL404487 0.90 MEN1 (0.85) CHRNA7CYP3A4ALOX15CHRNB2NFKB1
SCHEMBL10105152 0.81 CHRNA7 (0.72) CHRNA7CYP3A4ALOX15CHRNB2NFKB1
SCHEMBL6743986 0.78 ALOX15 (0.64) CHRNA7CYP3A4ALOX15CHRNB2NFKB1
SCHEMBL10105155 0.78 CHRNA7 (0.63) CHRNA7CYP3A4ALOX15CHRNB2NFKB1
SCHEMBL576454 0.77 LMNA (0.67) CHRNA7CYP3A4ALOX15CHRNB2NFKB1
SCHEMBL164538 0.77 LMNA (0.67) CHRNA7CYP3A4ALOX15CHRNB2NFKB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 109 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1610714-A Polycarbonate-siloxane copolymers GEN ELECTRIC (US) 2005-04-27 CN claimed
EP-0743574-B1 Migration imaging members XEROX CORP (US) 2000-12-27 EP claimed
EP-0743573-B1 Method for obtaining image contrast migration imaging members XEROX CORP (US) 2000-09-06 EP claimed
EP-0831772-A2 INTRAURETHRAL PHARMACOTHERAPY OF INCONTINENCE IOTEK, INC. (US) 1998-04-01 EP claimed
EP-0615855-B1 Recording sheets containing pyridinium and/or piperazinum compounds XEROX CORP (US) 1997-05-14 EP claimed
WO-1996040054-A2 INTRAURETHRAL PHARMACOTHERAPY OF INCONTINENCE IOTEK, INC. (US) 1996-12-19 WO claimed
US-20250221923-A1 BOOSTING OSMOTIC BLOOD-ORGAN BARRIER OPENING FOR IMPROVED DELIVERY OF THERAPEUTICS TO ORGANS UNIVERSITY OF MARYLAND, BALTIMORE 2025-07-10 US disclosed
US-20240359168-A1 Mesoporous Catalyst Compounds and Uses Thereof EXXONMOBIL RESEARCH AND ENGINEERING COMPANY 2024-10-31 US disclosed
US-12064752-B2 Mesoporous catalyst compounds and uses thereof ExxonMobil Technology and Engineering Company (US) 2024-08-20 US disclosed
US-20240009269-A1 MEMBRANE-ACTIVE PEPTIDES AND METHODS FOR REVERSIBLE BLOOD- BRAIN BARRIER OPENING THE JOHNS HOPKINS UNIVERSITY (US) 2024-01-11 US disclosed
US-11774853-B2 Resist composition and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-10-03 US disclosed
US-11733608-B2 Resist composition and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-08-22 US disclosed
US-11720018-B2 Chemically amplified resist composition and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-08-08 US disclosed
US-4306085-A Hydroformylation process using resin-ligand-metal catalyst SHELL OIL COMPANY (US) 1981-12-15 US disclosed
EP-0005569-B1 RESIN-LIGAND-TRANSITION METAL COMPLEX COMPOSITION AND PROCESSES FOR USING THIS COMPOSITION AS CATALYST SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1981-11-04 EP disclosed
EP-0002557-B1 RESIN-LIGAND TRANSITION METAL COMPLEX COMPOSITION AND PROCESSES FOR USING THIS COMPOSITION AS CATALYST SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1981-09-23 EP disclosed
US-4284835-A METAL COMPLEX CATALYST BOUND TO RESIN SHELL OIL COMPANY (US) 1981-08-18 US disclosed
US-4266085-A Olefin disproportionation process SHELL OIL COMPANY (US) 1981-05-05 US disclosed
US-4179402-A Resin-metal-ligand composition SHELL OIL COMPANY (US) 1979-12-18 US disclosed
US-4179403-A Resin-ligand-metal complex compositions SHELL OIL COMPANY (US) 1979-12-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11733608-B2 Resist composition and patterning process HNRNPU, INSR, BICRA CHRNA7 2834/4885CYP3A4 4628/4885ALOX15 2664/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.