Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 6/20 | 0.38 |
| ▸ | CYP4F2 | P78329 | 3/20 | 0.38 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
| ▸ | MME | P08473 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3016489 | 1.00 | ZDHHC7 (0.46) | ZDHHC7CA1CA2ACHECYP4F2 | |
| SCHEMBL5749745 | 0.91 | CA1 (0.42) | ZDHHC7CA1CA2ACHECYP4F2 | |
| SCHEMBL5694365 | 0.91 | ZDHHC7 (0.52) | ZDHHC7CA1CA2TDP1ABCB1 | |
| SCHEMBL8586333 | 0.90 | ZDHHC7 (0.42) | ZDHHC7CA1CA2ACHECYP4F2 | |
| SCHEMBL11648130 | 0.89 | ZDHHC7 (0.48) | ZDHHC7CA1CA2TDP1ABCB1 | |
| SCHEMBL27745855 | 0.85 | TDP1 (0.45) | ZDHHC7CA1CA2CYP4F2CYP4A11 | |
| SCHEMBL27745858 | 0.85 | TDP1 (0.45) | ZDHHC7CA1CA2CYP4F2CYP4A11 | |
| SCHEMBL31079658 | 0.84 | ZDHHC7 (0.38) | ZDHHC7CA1CA2ACHECYP4F2 | |
| SCHEMBL29825333 | 0.84 | ZDHHC7 (0.38) | ZDHHC7CA1CA2ACHECYP4F2 | |
| SCHEMBL11650719 | 0.84 | CA1 (0.46) | ZDHHC7CA1CA2TDP1ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2268319-A2 | PRECURSORS OF LIPID METABOLISM FOR THE DIAGNOSIS AND TREATMENT OF CANCER | Universität Ulm (DE) | 2011-01-05 | — | — | EP | disclosed |
| WO-2009109798-A2 | PRECURSORS OF LIPID METABOLISM FOR THE DIAGNOSIS AND TREATMENT OF CANCER | UNIVERSITÄT ULM (DE) | 2009-09-11 | — | — | WO | disclosed |