Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 6/20 | 0.32 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.32 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.32 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29825333 | 0.87 | ZDHHC7 (0.38) | ZDHHC7CA1CA2ACHECYP4F2 | |
| SCHEMBL16547562 | 0.85 | ZDHHC7 (0.37) | ZDHHC7CA1CA2ALDH1A1ABCB1 | |
| SCHEMBL3016489 | 0.84 | ZDHHC7 (0.46) | ZDHHC7CA1CA2ACHECYP4F2 | |
| SCHEMBL1010540 | 0.84 | ZDHHC7 (0.46) | ZDHHC7CA1CA2ACHECYP4F2 | |
| SCHEMBL31079577 | 0.83 | ZDHHC7 (0.34) | ZDHHC7CA1CA2ALDH1A1ABCB1 | |
| SCHEMBL28156113 | 0.79 | GPR84 (0.36) | ZDHHC7ALDH1A1ACHECYP4F2CYP4A11 | |
| SCHEMBL27614024 | 0.79 | GPR84 (0.36) | ZDHHC7ALDH1A1ACHECYP4F2CYP4A11 | |
| SCHEMBL28290657 | 0.79 | GPR84 (0.36) | ZDHHC7ALDH1A1ACHECYP4F2CYP4A11 | |
| SCHEMBL3691540 | 0.79 | GPR84 (0.36) | ZDHHC7ALDH1A1ACHECYP4F2CYP4A11 | |
| SCHEMBL8586333 | 0.79 | ZDHHC7 (0.42) | ZDHHC7CA1CA2ACHECYP4F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240341301-A1 | ITACONATE AND DERIVATIVES THEREOF FOR THE PROTECTION OF CELLS, TISSUES, AND ORGANS | UNIV MICHIGAN REGENTS (US) | 2024-10-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240341301-A1 | ITACONATE AND DERIVATIVES THEREOF FOR THE PROTECTION OF CELLS, TISSUES, AND ORGANS | TNNI3, ALDH2, ALDH5A1 | ZDHHC7 811/4885CA1 1769/4885CA2 2897/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.