SCHEMBL10105994

SCHEMBL10105994

CC(C)c1n[nH]c(/N=N/c2c(C(C)(C)C)nn(-c3ccccc3)c2O)c1C#N

nearest known ligand 0.32

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.32
MAPT P10636 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
RIPK1 Q13546 1/20 0.31
GAA P10253 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12363889 0.89 ATM (0.34) KDM4EMAPTNPSR1GAA
SCHEMBL12363233 0.85 GAA (0.42) KDM4EMAPTNPSR1GAA
SCHEMBL12363894 0.84
SCHEMBL10105984 0.83 MAPT (0.39) KDM4EMAPTNPSR1GAA
SCHEMBL10101675 0.83 RIPK1 (0.31) RIPK1
SCHEMBL10105981 0.83
SCHEMBL12363234 0.81 KDM4E (0.36) KDM4EMAPTNPSR1GAA
SCHEMBL12363243 0.80 KDM4E (0.30) KDM4EMAPTNPSR1
SCHEMBL12362880 0.80 GRM5 (0.36) KDM4EMAPTNPSR1
SCHEMBL12363228 0.79 KDM4E (0.37) KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8808824-B2 Optical information recording medium, method of recording information and azo metal complex dye FUJIFILM CORPORATION (JP) 2014-08-19 US disclosed
US-8092890-B2 Optical information recording medium, method of recording information, and azo metal complex dye FUJIFILM CORPORATION (JP) 2012-01-10 US disclosed
US-20110202942-A1 OPTICAL INFORMATION RECORDING MEDIUM, METHOD OF RECORDING INFORMATION AND PHOTOSENSITIZER FUJIFILM CORPORATION (JP) 2011-08-18 US disclosed
US-20110177281-A1 OPTICAL INFORMATION RECORDING MEDIUM, METHOD OF RECORDING INFORMATION AND AZO METAL COMPLEX DYE FUJIFILM CORPORATION (JP) 2011-07-21 US disclosed
US-20080254252-A1 OPTICAL INFORMATION RECORDING MEDIUM, METHOD OF RECORDING INFORMATION, AND AZO METAL COMPLEX DYE FUJIFILM CORPORATION (JP) 2008-10-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110202942-A1 OPTICAL INFORMATION RECORDING MEDIUM, METHOD OF RECORDING INFORMATION AND PHOTOSENSITIZER KCNN4, IK, KCNJ2 KDM4E 2051/4885MAPT 977/4885NPSR1 1433/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.