SCHEMBL10106249

SCHEMBL10106249

CCCCn1c(O)c(/N=N/c2[nH]nc(C(C)(C)C)c2C#N)c(C)c(C#N)c1=O

nearest known ligand 0.38

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MAPT P10636 10/20 0.38
MEN1 O00255 9/20 0.38
KMT2A Q03164 9/20 0.38
KDM4E B2RXH2 6/20 0.36
ALDH1A1 P00352 5/20 0.36
HSD17B10 Q99714 3/20 0.36
TSHR P16473 2/20 0.36
CASP1 P29466 1/20 0.36
PKM P14618 1/20 0.35
MITF O75030 1/20 0.33
THRB P10828 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
HPGD P15428 1/20 0.32
TAAR1 Q96RJ0 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
GRM2 Q14416 1/20 0.31
ALPL P05186 1/20 0.30
ALPG P10696 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10105996 0.86 MAPT (0.39) MAPTMEN1KMT2AKDM4EALDH1A1
SCHEMBL12513974 0.78 MAPT (0.41) MAPTMEN1KMT2AKDM4EALDH1A1
SCHEMBL10101652 0.78 ALDH1A1 (0.31) MAPTKMT2AALDH1A1
SCHEMBL12363895 0.78 MAPT (0.40) MAPTMEN1KMT2AKDM4EALDH1A1
SCHEMBL10106258 0.76 MAPT (0.36) MAPTMEN1KMT2AALDH1A1SMN1; SMN2
SCHEMBL13996970 0.76 MAPT (0.36) MAPTMEN1KMT2AALDH1A1SMN1; SMN2
SCHEMBL13927285 0.75 MAPT (0.39) MAPTMEN1KMT2AKDM4EALDH1A1
SCHEMBL9011514 0.75 MEN1 (0.46) MAPTMEN1KMT2AKDM4EALDH1A1
SCHEMBL13539155 0.74 MAPT (0.40) MAPTMEN1KMT2AKDM4EALDH1A1
SCHEMBL13927273 0.74 MAPT (0.38) MAPTMEN1KMT2AKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8092890-B2 Optical information recording medium, method of recording information, and azo metal complex dye FUJIFILM CORPORATION (JP) 2012-01-10 US disclosed
US-20110202942-A1 OPTICAL INFORMATION RECORDING MEDIUM, METHOD OF RECORDING INFORMATION AND PHOTOSENSITIZER FUJIFILM CORPORATION (JP) 2011-08-18 US disclosed
US-20080310293-A1 OPTICAL INFORMATION RECORDING MEDIUM AND METHOD OF RECORDING INFORMATION FUJIFILM CORPORATION (JP) 2008-12-18 US disclosed
US-20080254252-A1 OPTICAL INFORMATION RECORDING MEDIUM, METHOD OF RECORDING INFORMATION, AND AZO METAL COMPLEX DYE FUJIFILM CORPORATION (JP) 2008-10-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110202942-A1 OPTICAL INFORMATION RECORDING MEDIUM, METHOD OF RECORDING INFORMATION AND PHOTOSENSITIZER KCNN4, IK, KCNJ2 MAPT 977/4885MEN1 731/4885KMT2A 699/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.