SCHEMBL1010677

SCHEMBL1010677

C=COOOOCCCCCCCC

nearest known ligand 0.38

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.38
LPAR1 Q92633 3/20 0.34
LPAR3 Q9UBY5 3/20 0.34
LPAR2 Q9HBW0 2/20 0.34
THRB P10828 2/20 0.33
MEN1 O00255 1/20 0.33
HTT P42858 1/20 0.33
KMT2A Q03164 1/20 0.33
MAPT P10636 1/20 0.33
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA9 Q16790 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31318108 1.00 TSHR (0.38) TSHRLPAR1LPAR3LPAR2THRB
SCHEMBL7155138 1.00 TSHR (0.38) TSHRLPAR1LPAR3LPAR2THRB
SCHEMBL10524053 0.98 TSHR (0.37) TSHRLPAR1LPAR3LPAR2THRB
SCHEMBL15350859 0.98 TSHR (0.37) TSHRLPAR1LPAR3LPAR2THRB
SCHEMBL15351783 0.98 TSHR (0.37) TSHRLPAR1LPAR3LPAR2THRB
SCHEMBL15350980 0.98 TSHR (0.37) TSHRLPAR1LPAR3LPAR2THRB
SCHEMBL5265569 0.98 TSHR (0.37) TSHRLPAR1LPAR3LPAR2THRB
SCHEMBL9442715 0.98 TSHR (0.37) TSHRLPAR1LPAR3LPAR2THRB
SCHEMBL380862 0.98 TSHR (0.37) TSHRLPAR1LPAR3LPAR2THRB
SCHEMBL15351768 0.98 TSHR (0.37) TSHRLPAR1LPAR3LPAR2THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7943067-B2 A polymerized hydrogel particles are first encapsulated the hydrogel-forming components into liposomes; drug delivery, drug targeting, protein separation, enzyme immobilization POLYTECHNIC INSTITUTE OF NEW YORK UNIVERSITY (US) 2011-05-17 US claimed
EP-1425112-B1 Method of manufacturing hydrogel particles of nano size UNIV POLYTECHNIC (US) 2009-06-17 EP claimed
EP-1425112-A4 NANOGELS AND THEIR PRODUCTION USING LIPOSOMES AS REACTORS UNIV POLYTECHNIC (US) 2005-06-15 EP claimed
US-20040203091-A1 Process for synthesizing protein using cell-free protein synthesis system RIKEN (JP) 2004-10-14 US claimed
EP-1425112-A1 NANOGELS AND THEIR PRODUCTION USING LIPOSOMES AS REACTORS POLYTECHNIC UNIVERSITY (US) 2004-06-09 EP claimed
EP-1384778-A1 PROCESS FOR SYNTHESIZING PROTEIN USING CELL-FREE PROTEIN SYNTHESIS SYSTEM RIKEN (JP) 2004-01-28 EP claimed
US-20030044455-A1 Nanogels and their production using liposomes as reactors POLYTECHNIC INSTITUTE OF NEW YORK UNIVERSITY 2003-03-06 US claimed
WO-2003015936-A1 NANOGELS AND THEIR PRODUCTION USING LIPOSOMES AS REACTORS POLYTECHNIC UNIVERSITY (US) 2003-02-27 WO claimed
WO-2025122719-A1 DIALYSIS-BASED METHOD FOR AFFINITY MAPPING OF CHROMATIN INTERACTIONS CZ BIOHUB SF, LLC (US) 2025-06-12 WO disclosed
US-11618777-B2 Method of manufacturing membrane protein and utilization thereof Yokoyama, Shigeyuki (JP) 2023-04-04 US disclosed
US-20210055188-A1 METHODS FOR ISOLATING, DETECTING, AND/OR ANALYZING ANTIBODIES FROM A FORMALIN FIXED PARAFFIN EMBEDDED (FFPE) TISSUE SAMPLE SHIMADZU CORPORATION (JP) 2021-02-25 US disclosed
US-20190194286-A1 METHOD OF MANUFACTURING MEMBRANE PROTEIN AND UTILIZATION THEREOF YOKOYAMA, SHIGEYUKI (JP) 2019-06-27 US disclosed
EP-2841040-B1 ABSORBENT ARTICLE COMPRISING WATER-ABSORBENT RESIN POWDER LIVEDO CORP (JP) 2018-07-11 EP disclosed
EP-2841040-A1 ABSORBENT ARTICLE COMPRISING WATER-ABSORBENT RESIN POWDER Livedo Corporation (JP) 2015-03-04 EP disclosed
US-20030044455-A1 Nanogels and their production using liposomes as reactors POLYTECHNIC INSTITUTE OF NEW YORK UNIVERSITY 2003-03-06 US disclosed
WO-2003015936-A1 NANOGELS AND THEIR PRODUCTION USING LIPOSOMES AS REACTORS POLYTECHNIC UNIVERSITY (US) 2003-02-27 WO disclosed
US-5952312-A TOPICALLY APPLYING NADH OR NADPH, OR A PHYSIOLOGICALLY ACCEPTABLE SALT THEREOF, TO THE SKIN OF A PERSON TO STIMULATE ATP PRODUCTION OF THE SKIN CELLS, WHEREIN THE NADH OR NADPH OR SALT IS STABILIZED AGAINST OXIDATION BIRKMAYER PHARMACEUTICALS, INC. (US) 1999-09-14 US disclosed
US-5750512-A FOR TREATMENT OF PARKINSON'S AND ALZHEIMER'S DISEASE OR MENTAL DEPRESSION BIRKMAYER PHARMACEUTICALS, INC. (US) 1998-05-12 US disclosed
US-5654288-A OXIDATION RESISTANCE BIRKMAYER PHARMACEUTICALS, INC. (US) 1997-08-05 US disclosed
EP-0722734-A1 NADH and NADPH therapeutic agents for nasal, sublingual, rectal and dermal administration BIRKMAYER U.S.A. (US) 1996-07-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030044455-A1 Nanogels and their production using liposomes as reactors PHOSPHO1, LIPA, PLD1 TSHR 3957/4885LPAR1 99/4885LPAR3 132/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.