Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | TP53 | P04637 | 3/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2137461 | 0.87 | TSHR (0.55) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL63104 | 0.79 | TSHR (0.64) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL5835079 | 0.77 | TSHR (0.57) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL13129209 | 0.75 | TSHR (0.53) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL2133150 | 0.75 | TSHR (0.53) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL23466722 | 0.75 | TSHR (0.53) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL10606391 | 0.75 | TSHR (0.53) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL5701982 | 0.74 | TSHR (0.49) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL476966 | 0.74 | TSHR (0.61) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL31218509 | 0.72 | TSHR (0.55) | TSHRALDH1A1TP53HIF1AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1201672-B1 | Organosilicon compound | SHINETSU CHEMICAL CO (JP) | 2011-01-05 | — | — | EP | disclosed |
| EP-1231241-B1 | Dual curable organopolysiloxane composition | SHINETSU CHEMICAL CO (JP) | 2010-11-03 | — | — | EP | disclosed |
| US-7045572-B2 | Organosilicon compound | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2006-05-16 | — | — | US | disclosed |
| US-20050101791-A1 | Organosilicon compound | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2005-05-12 | — | — | US | disclosed |
| US-6849755-B2 | Organosilicon compound | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2005-02-01 | — | — | US | disclosed |
| US-6699918-B2 | DIHYDROXYPOLYSILOXANE, ACRYLATED SILOXANE COMPOUND, AND BOTH A PHOTOPOLYMERIZATION INITIATOR AND A CONDENSATION CURING CATALYST; ADHESION TO A SUBSTRATE IMMEDIATELY FOLLOWING IRRADIATION | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2004-03-02 | — | — | US | disclosed |
| US-20020151616-A1 | Dihydroxypolysiloxane, acrylated siloxane compound, and both a photopolymerization initiator and a condensation curing catalyst; adhesion to a substrate immediately following irradiation | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2002-10-17 | — | — | US | disclosed |
| EP-1231241-A1 | Dual curable organopolysiloxane composition | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2002-08-14 | — | — | EP | disclosed |
| US-20020099232-A1 | Organosilicon compound | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2002-07-25 | — | — | US | disclosed |
| EP-1201672-A2 | Organosilicon compound | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2002-05-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050101791-A1 | Organosilicon compound | H1-0, H1-2, H1-4 | TSHR 2447/4885ALDH1A1 3552/4885TP53 2216/4885 |
| US-20020099232-A1 | Organosilicon compound | H1-0, H1-4, H1-2 | TSHR 3723/4885ALDH1A1 3248/4885TP53 3077/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.