Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | PRKCQ | Q04759 | 11/20 | 0.43 |
| ▸ | PRKCA | P17252 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.37 |
| ▸ | MAT2A | P31153 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | FEN1 | P39748 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL527382 | 0.84 | SMN1; SMN2 (0.56) | DAOALDH1A1PRKCQPRKCANPC1 | |
| SCHEMBL530180 | 0.81 | DAO (0.54) | DAOALDH1A1PRKCQPRKCASMN1; SMN2 | |
| SCHEMBL21385026 | 0.75 | DAO (0.52) | DAOALDH1A1PRKCQFEN1 | |
| SCHEMBL11511885 | 0.75 | DAO (0.58) | DAOALDH1A1PRKCQPRKCAGAA | |
| SCHEMBL30377628 | 0.74 | DAO (0.50) | DAOALDH1A1PRKCQPRKCAADORA3 | |
| SCHEMBL22090020 | 0.72 | KDM4E (0.53) | DAOALDH1A1 | |
| SCHEMBL10108726 | 0.71 | DAO (0.50) | DAOALDH1A1PRKCQPRKCAADORA3 | |
| SCHEMBL23253066 | 0.70 | PRKCQ (0.54) | DAOALDH1A1PRKCQPRKCAADORA3 | |
| SCHEMBL30257859 | 0.70 | DAO (0.55) | DAOALDH1A1PRKCQPRKCAADORA3 | |
| SCHEMBL28492436 | 0.69 | SMN1; SMN2 (0.57) | DAOALDH1A1NPC1GAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012015693-A1 | IMIDAZOLE DERIVATIVES | MERCK SHARP & DOHME CORP. (US) | 2012-02-02 | — | — | WO | disclosed |