Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.54 |
| ▸ | PRKCQ | Q04759 | 10/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | GSK3B | P49841 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | PRKCA | P17252 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CALCRL | Q16602 | 1/20 | 0.41 |
| ▸ | FEN1 | P39748 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11511885 | 0.85 | DAO (0.58) | DAOPRKCQALDH1A1GSK3BPRKCA | |
| SCHEMBL10108726 | 0.83 | DAO (0.50) | DAOPRKCQALDH1A1PRKCAL3MBTL1 | |
| SCHEMBL10108899 | 0.81 | DAO (0.46) | DAOPRKCQALDH1A1SMN1; SMN2PRKCA | |
| SCHEMBL527382 | 0.81 | SMN1; SMN2 (0.56) | DAOPRKCQALDH1A1GSK3BKDM4E | |
| SCHEMBL23253066 | 0.80 | PRKCQ (0.54) | DAOPRKCQALDH1A1PRKCAMEN1 | |
| SCHEMBL527340 | 0.78 | DAO (0.54) | DAOALDH1A1GSK3BKDM4ESMN1; SMN2 | |
| SCHEMBL30377628 | 0.78 | DAO (0.50) | DAOPRKCQALDH1A1PRKCA | |
| SCHEMBL30257859 | 0.77 | DAO (0.55) | DAOPRKCQALDH1A1PRKCAFEN1 | |
| SCHEMBL16634744 | 0.77 | L3MBTL1 (0.55) | DAOGSK3BKDM4ESMN1; SMN2MEN1 | |
| SCHEMBL30079630 | 0.75 | DAO (0.50) | DAOPRKCQALDH1A1PRKCAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012015693-A1 | IMIDAZOLE DERIVATIVES | MERCK SHARP & DOHME CORP. (US) | 2012-02-02 | — | — | WO | disclosed |