Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.73 |
| ▸ | THRB | P10828 | 1/20 | 0.73 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.73 |
| ▸ | CA2 | P00918 | 8/20 | 0.64 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.58 |
| ▸ | FYN | P06241 | 1/20 | 0.58 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.58 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.58 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.58 |
| ▸ | DRD4 | P21917 | 1/20 | 0.58 |
| ▸ | DRD3 | P35462 | 1/20 | 0.58 |
| ▸ | CA12 | O43570 | 7/20 | 0.57 |
| ▸ | CA1 | P00915 | 6/20 | 0.57 |
| ▸ | CA9 | Q16790 | 5/20 | 0.57 |
| ▸ | CA4 | P22748 | 2/20 | 0.53 |
| ▸ | CA5A | P35218 | 2/20 | 0.53 |
| ▸ | CA7 | P43166 | 2/20 | 0.53 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18392671 | 1.00 | CYP2D6 (0.73) | CYP2D6THRBHSD17B10CA2TSHR | |
| SCHEMBL2614764 | 1.00 | CYP2D6 (0.73) | CYP2D6THRBHSD17B10CA2TSHR | |
| SCHEMBL16136863 | 1.00 | CYP2D6 (0.73) | CYP2D6THRBHSD17B10CA2TSHR | |
| SCHEMBL14478545 | 1.00 | CYP2D6 (0.73) | CYP2D6THRBHSD17B10CA2TSHR | |
| SCHEMBL7152247 | 1.00 | CYP2D6 (0.73) | CYP2D6THRBHSD17B10CA2TSHR | |
| SCHEMBL23266161 | 1.00 | CYP2D6 (0.73) | CYP2D6THRBHSD17B10CA2TSHR | |
| SCHEMBL2629591 | 1.00 | CYP2D6 (0.73) | CYP2D6THRBHSD17B10CA2TSHR | |
| SCHEMBL21945978 | 1.00 | CYP2D6 (0.73) | CYP2D6THRBHSD17B10CA2TSHR | |
| SCHEMBL22330671 | 1.00 | CYP2D6 (0.73) | CYP2D6THRBHSD17B10CA2TSHR | |
| SCHEMBL133205 | 1.00 | CYP2D6 (0.73) | CYP2D6THRBHSD17B10CA2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9975911-B2 | Antibacterial compounds and biological applications thereof | MUTABILIS (FR) | 2018-05-22 | — | — | US | disclosed |
| US-20140178923-A1 | TRICLOSAN DERIVATIVES AND USES THEREOF | OXOID LIMITED (GB) | 2014-06-26 | — | — | US | disclosed |
| US-20120022012-A1 | Glycosylated Acetaminophen Pro-Drug Analogs | NuTek Pharma Ltd. | 2012-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140178923-A1 | TRICLOSAN DERIVATIVES AND USES THEREOF | CD14, ABCG2, PTPN22 | CYP2D6 697/4885THRB 512/4885HSD17B10 819/4885 |
| US-20120022012-A1 | Glycosylated Acetaminophen Pro-Drug Analogs | UGT1A3, GCG, UGT1A1 | CYP2D6 11/4885THRB 3123/4885HSD17B10 799/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.