SCHEMBL10109752

SCHEMBL10109752

Cc1ccc(-c2ccc(Nc3ccc(-n4c5ccccc5c5ccccc54)cc3)cc2)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 1/20 0.48
KDM4E B2RXH2 1/20 0.48
ATM Q13315 1/20 0.48
L3MBTL1 Q9Y468 1/20 0.48
AKR1C4 P17516 1/20 0.43
AKR1C3 P42330 1/20 0.43
AKR1C2 P52895 1/20 0.43
AKR1C1 Q04828 1/20 0.43
HDAC4 P56524 1/20 0.43
MAPT P10636 5/20 0.41
LMNA P02545 2/20 0.41
HTT P42858 1/20 0.41
KDM1A O60341 1/20 0.41
MAPK1 P28482 3/20 0.40
NPSR1 Q6W5P4 2/20 0.40
TP53 P04637 2/20 0.39
ABCG2 Q9UNQ0 1/20 0.39
ALDH1A1 P00352 3/20 0.39
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23620635 0.95 L3MBTL1 (0.53) HPGDKDM4EATML3MBTL1AKR1C4
SCHEMBL14902282 0.90 HPGD (0.44) HPGDKDM4EATML3MBTL1AKR1C4
SCHEMBL14029467 0.90 HPGD (0.47) HPGDKDM4EATML3MBTL1AKR1C4
SCHEMBL16369086 0.90 KDM4E (0.59) HPGDKDM4EATML3MBTL1AKR1C4
SCHEMBL2607402 0.90 KDM4E (0.59) HPGDKDM4EATML3MBTL1AKR1C4
SCHEMBL14049561 0.89 KDM4E (0.49) HPGDKDM4EATML3MBTL1AKR1C4
SCHEMBL23423503 0.88 L3MBTL1 (0.59) HPGDKDM4EATML3MBTL1AKR1C4
SCHEMBL23423507 0.88 L3MBTL1 (0.59) HPGDKDM4EATML3MBTL1AKR1C4
SCHEMBL21905511 0.88 L3MBTL1 (0.59) HPGDKDM4EATML3MBTL1AKR1C4
SCHEMBL12249880 0.88 L3MBTL1 (0.59) HPGDKDM4EATML3MBTL1AKR1C4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120074395-A1 ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2012-03-29 US disclosed