Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IAPP | P10997 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 6/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | F2R | P25116 | 2/20 | 0.37 |
| ▸ | MPO | P05164 | 1/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12261416 | 0.84 | FFAR1 (0.55) | FFAR1FFAR4PKM | |
| SCHEMBL1405167 | 0.81 | IAPP (0.50) | IAPPFFAR1FFAR4ALDH1A1LMNA | |
| SCHEMBL8231223 | 0.81 | NPSR1 (0.44) | IAPPFFAR1FFAR4ALDH1A1LMNA | |
| SCHEMBL28688067 | 0.81 | FFAR4 (0.46) | IAPPFFAR4ALDH1A1LMNAPKM | |
| SCHEMBL31248058 | 0.80 | CYP4F2 (0.50) | FFAR1FFAR4ALDH1A1LMNAKDM4E | |
| SCHEMBL25386733 | 0.79 | IAPP (0.41) | IAPPFFAR4ALDH1A1LMNAKDM4E | |
| SCHEMBL31627780 | 0.79 | MTNR1A (0.57) | MTNR1AMTNR1BNOTUM | |
| SCHEMBL534533 | 0.79 | MTNR1A (0.57) | MTNR1AMTNR1BNOTUM | |
| SCHEMBL21222818 | 0.79 | MAOB (0.53) | IAPPFFAR1FFAR4RIPK1MAOB | |
| SCHEMBL30488619 | 0.79 | MAOB (0.53) | IAPPFFAR1FFAR4RIPK1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2409984-A1 | Dimeric IAP Antagonists | TETRALOGIC PHARMACEUTICALS CORPORATION (US) | 2012-01-25 | — | — | EP | disclosed |