Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | NT5E | P21589 | 1/20 | 0.34 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.33 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.32 |
| ▸ | CCR5 | P51681 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13787024 | 0.85 | CTSK (0.35) | POLB | |
| SCHEMBL820248 | 0.80 | BCHE (0.39) | BCHERAB9ANPC1SMN1; SMN2POLB | |
| SCHEMBL13787023 | 0.80 | BCHE (0.39) | BCHERAB9ANPC1SMN1; SMN2POLB | |
| SCHEMBL379870 | 0.80 | BCHE (0.39) | BCHERAB9ANPC1SMN1; SMN2POLB | |
| SCHEMBL10860763 | 0.76 | POLB (0.48) | BCHERAB9ANPC1SMN1; SMN2POLB | |
| SCHEMBL10368703 | 0.76 | POLB (0.48) | BCHERAB9ANPC1SMN1; SMN2POLB | |
| SCHEMBL10367964 | 0.75 | POLB (0.48) | BCHERAB9ANPC1SMN1; SMN2POLB | |
| SCHEMBL10860120 | 0.75 | POLB (0.48) | BCHERAB9ANPC1SMN1; SMN2POLB | |
| SCHEMBL10390427 | 0.75 | POLB (0.45) | BCHERAB9ASMN1; SMN2POLBMAPT | |
| SCHEMBL10863400 | 0.72 | POLB (0.46) | BCHERAB9ANPC1SMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2409984-A1 | Dimeric IAP Antagonists | TETRALOGIC PHARMACEUTICALS CORPORATION (US) | 2012-01-25 | — | — | EP | disclosed |